IRCT2015120625384N1 IRCT 2016-01-24 Behjoo Brain Center Efficacy of transcranial direct current stimulation in reduction of anxiety and crystalline heroin craving. The efficacy of transcranial direct current stimulation of dorsolateral prefrontal cortex on modulation of anxiety and craving in crystalline heroin dependents in MMT program. 2015-12-22 anticipated 40 Complete https://irct.ir/trial/21250 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Other, Purpose: Treatment. N/A Crystalline Heroin Dependence. Intervention 1: Direct current will be delivered from a constant current stimulator (ActivaDose), and will be transferred by a pair of (35 cm2) electrodes with stimulation intensity of 2mA. Electrodes are standard carbonic, covered with a normal saline soaked sponge cases. In current stimulations (right anodal/left cathodal), the anod electrod will be placed on the right DLPFC (F4), and the cathode electrod will be placed on the left DLPFC (F3). In current stimulations (right cathodal/left anodal), the cathod electrod will be placed on the right DLPFC (F4), and the anod electrod will be placed on the left DLPFC (F3). The stimulation will be performed randomly for subjects in the experimental group during 2 sessions. Subjects in experimental groups will receive sham stimulation at first session. The only difference in this kind of stimulation is that the current will cut after 30s and primarily itching and sting will be felt by the subject. The Stimulation will be done for 20min. To omit the carry over effect of multiple stimulations, the experiments were performed at 72 hrs intervals. Intervention 2: Direct current will be delivered from a constant current stimulator (ActivaDose), and will be transferred by a pair of (35 cm2) electrodes with stimulation intensity of 2mA. Electrodes are standard carbonic, covered with a normal saline soaked sponge cases. Subjects in control group will receive sham stimulation in 1 session. The only difference in this kind of stimulation is that the current will cut after 30s and primarily itching and sting will be felt by the subject. The Stimulation will be done for 20min.