IRCT2015112425217N1 IRCT 2016-01-31 Vice Chancellery for Research of Mashhad University of Medical Sciences Effect of a herbal medicine combinations in the treatment of chronic sinusitis TPM: Traditional Persian Medicine, EP3OS: European Position Paper on Rhinosinusitis and Nasal Polyp Elucidation of sinusitis based on Traditional Persian Medicine (TPM) and comparison of the TPM therapeutic protocol efficacy on chronic sinusitis with classic treatment: Mixed Methods 2015-12-22 anticipated 52 Complete https://irct.ir/trial/21121 interventional Randomization: Not randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. 3 Chronic sinusitis. Intervention 1: Intervention group: Oral drug: Marjoram and licorice herbal tea, dose: 5 grams of pack contains 3 grams of leaves of marjoram and 2 grams of licorice root, every 8 hours, the duration of treatment (consumption): 8 weeks; If there is no improvement in symptoms for up to 12 weeks will continue. How to use: patient should be infuse the contents of each packet with 200 ml of boiling water in the pot for 20 minutes and after clearing, to be drink slowly at a temperature close lukewarm to hot , divided by maintaining an hour away from food, . Local drug: Lavender oil on base of olive oil, dosage: 3-2 drops once a day (at night), the duration of treatment (consumption): 8 weeks; if there is no improvement in symptoms for up to 12 weeks will continue. Education: patients of this group on the basis of written instructions that will be placed at their disposal, will be avoided from harmful foods for cold and catarrh (such as yogurt, buttermilk, cheese, dough bread , bananas, vinegar, ...). Intervention 2: Control group: Prescription drugs include: Inhaled corticosteroid (Fluxinase), at a rate of 2 inhalations per day; along with daily nose irrigation with normal saline in the morning and evening. If there is no improvement, a systemic steroids will be administrated (prednisone tablets 1 mg / kg; that will be tapered within a short time). If there is evidence of purulent sinusitis, antibiotic treatment with azithromycin capsules of 250 mg daily for 4 weeks will be added to the treatment protocol.