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IRCT2015111825098N1 IRCT 2016-03-18 Vice Chancellor for research of Semnan University of Medical Sciences Comparison the analgesic efficacy of intramuscular morphine and morphine suppository in renal colic - Comparison the analgesic efficacy of intramuscular morphine and morphine suppository in patients with renal colic 2016-02-20 anticipated 84 Complete https://irct.ir/trial/21051 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. N/A renal colic. Intervention 1: Intervention group: Patients with renal colic that receive 10 mg intramuscular Morphine Sulfate (manufactured by Darou Pakhsh Pharmaceutical Co.) for control of pain. Intervention 2: Control group: Patients with renal colic that receive 10 mg suppository of Morphine Sulfate (brand name: Opirect, manufactured by Aburaihan Pharmaceutical Co.) for control of pain.
public Dr Arash Ardestani Zadeh
Kowsar hospital, Basij Blvd., Semnan
Semnan Iran (Islamic Republic of) 3519899951 +98 23 3343 7830 ardestani_a@yahoo.com Semnan University of Medical Sciences scientific Dr Arash Ardestani Zadeh
Kowsar hospital, Basij Blvd., Semnan
Semnan Iran (Islamic Republic of) 3519899951 +98 23 3343 7830 ardestani_a@yahoo.com Semnan University of Medical Sciences Iran (Islamic Republic of) Inclusion criteria: 18-55 years old patients with unilateral acute flank or abdominal colicky pain that in evaluation of the patient with ultrasonography, CT scan or intravenous pyelography presence of the urinary stone is approved or the patient passes the stone. Exclusion criteria : sensitivity to morphine; addiction; fever higher than 38 degrees of centigrade; unstable hemodynamic condition; impaired hepatic or renal function; heart failure; respiratory failure; suspected to peritonitis; pregnancy or suspected to pregnancy; transplanted kidney; suspected to aneurysm or dissection of aorta and receiving analgesic within 6 hours before admission. 18 years 55 years Both N23 unspecified renal colic Treatment - Drugs Treatment - Drugs Intervention group: Patients with renal colic that receive 10 mg intramuscular Morphine Sulfate (manufactured by Darou Pakhsh Pharmaceutical Co.) for control of pain Control group: Patients with renal colic that receive 10 mg suppository of Morphine Sulfate (brand name: Opirect, manufactured by Aburaihan Pharmaceutical Co.) for control of pain Pain intensity. Timepoint: Before intervention, 15, 30 and 60 minutes after intervention. Method of measurement: Visual Analogue Scale. Blood pressure. Timepoint: Before intervention, 15, 30 and 60 minutes after intervention. Method of measurement: Sphygmomanometer. Heart rate. Timepoint: Before intervention, 15, 30 and 60 minutes after intervention. Method of measurement: Counting the number of radial pulse. Respiratory rate. Timepoint: Before intervention, 15, 30 and 60 minutes after intervention. Method of measurement: Counting the number of breaths. Nausea and Vomiting. Timepoint: Before intervention, 15, 30 and 60 minutes after intervention. Method of measurement: Question of the patient and observation. Dizziness. Timepoint: 15, 30 and 60 minutes after intervention. Method of measurement: Question of the patient. Drowsiness. Timepoint: 15, 30 and 60 minutes after intervention. Method of measurement: Observation. Facial Flushing. Timepoint: 15, 30 and 60 minutes after intervention. Method of measurement: Observation. Size of urinary stone. Timepoint: After intervention. Method of measurement: Imaging findings. Location of the stone. Timepoint: After intervention. Method of measurement: Imaging findings. Vice Chancellor for research of Semnan University of Medical Sciences Approved 2016-01-05 Ethics committee of Semnan University of Medical Sciences Central building of the university, Basij Blvd., Semnan Semnan Iran (Islamic Republic of)