IRCT2015072023253N1 IRCT 2016-08-17 Shahid Behsehti University of Medical Sciences Comparison of the anesthetic efficacy of articaine 4% in two supplemental anesthetic injections Comparison of the anesthetic efficacy of articaine 4% as supplemental intraligamentary injection with buccal infiltration in posterior mandibular teeth with irreversible pulpitis 2016-04-08 anticipated 100 Complete https://irct.ir/trial/19867 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Stratified permutations blocks randomization, Blinding description: All injections are done by a single clinician. The principle investigator or outcome assessor is different from the operator who administers anesthesia and root canal therapy. So he is blind to anesthetic technique used. The patients and the clinician who administered anesthesia are not blind to anesthetic technique. The statistician who analyzed the data was blinded to the procedure. 3 Irreversible pulpitis. Intervention 1: After inferior alveolar nerve block injection with lidocaine and epinephrine 1/80000, the supplemental buccal infiltration injection with articaine 4% and epinephrine 1/100000 will be done. Intervention 2: After inferior alveolar nerve block injection with lidocaine and epinephrine 1/80000, the intraligamentry injection with articaine 4% and epinephrine 1/100000 will be done. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is Because the article has not been published yet.