IRCT2015071323195N1 IRCT 2015-10-22 Tehran University of Medical Sciences International Campus, School of Nutritional Science and Diteti the effect of calorie restriction with medium fiber diet in obese and overweight type 2 diabetic patients apoa2=apolipoprotein a2 clinical trial of calorie restriction with medium fiber diet on serum levels of some inflammatory factors and their gene expression in obese and overweight type 2 diabetic patients with CC and TT/TC polymorphism in APOA-II and comparison of changes in these genotypes 2015-10-12 anticipated 28 Complete https://irct.ir/trial/19828 interventional Randomization: N/A, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Health service research. 2 Condition 1: non-insulin-dependent diabetes. Condition 2: obesity. During a 6-week patients will receive low-energy diet and moderate fiber (30 grams per day) including 55 to 65% carbohydrates, 20% protein and 25% fat. To get enough fiber in addition to increasing the consumption of fruits and vegetables will add wheat bran to the diet and to ensure the same type of bran consumption the required amount will be available to them every two weeks. After calculating the amount of energy needed for daily, diets will be set for each individual. 21 food menu with identified calorie will prepare for each personand every two weeks we will give them 7 menu with same calorie to the individuals which give them the power to choose the desired menu and even have a repeat in the week. And they also share the same energy that allows people to use between meals, such as breakfast menu to choose their favorite.