IRCT2015061822806N1 IRCT 2016-05-22 Vice chancellor for research, Mashhad University of Medical Sciences Effect of Iranian traditional medicine remedy on chemotherapy induced nausea and vomiting Effect of Iranian traditional medicine remedy compared with placebo on resistant chemotherapy induced nausea and vomiting in breast cancer 2015-10-03 anticipated 62 Complete https://irct.ir/trial/19594 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Crossover, Purpose: Treatment, Other design features: Random allocation and blinding was done this way: In the absence of research team, The laboratory expert, by using a computerized random number table,blindly allocated patients to intervention or control groups for second session chemotherapy in study. Hereafter, drug package codes were determined for patients. In cross over, the expert announced drug packages codes to researcher for delivery to the patients. Thus, this study is a randomized and double-blind. 2 Condition 1: Nausea and vomiting. Condition 2: Breast cancer. Condition 3: Follow-up examination after chemotherapy for other conditions. Intervention 1: 2.7 gram Persumac,plus one drop of black zirah essential oil made in Adonis Goldaroo,three time daily half hour before meal with one glass cold water. Intervention 2: 2.7 gram lactose, three time daily half hour before meal with one glass cold water. ااا