IRCT2015060622562N1 IRCT 2015-08-02 Vice chancellor for research, Kashan University of Medical Sciences The effect of selenium on nephropathy complications of diabetic patients The effects of selenium supplementation on advanced glycation end products, biomarkers of inflammatory and oxidative stress in diabetic nephropathy patients in comparison with placebo: a randomized double-blinded controlled clinical trial 2015-07-11 anticipated 60 Complete https://irct.ir/trial/19434 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: At study baseline and after stratification for pre-intervention BMI and age, subjects will be randomly divided into two groups to take either selenium supplements (n = 30) or placebo (n = 30). Randomization will be done by the use of computer-generated random numbers, Blinding description: Randomization and allocation will be concealed from the researchers and participants until the final analyses are completed. Another person at the Shahid Beheshti Clinic, who is not involved in the trial and not aware of random sequences, will be assigned the participants to the numbered bottles of capsules. 2 diabetic nephropathy. Intervention 1: Intervention: received one capsule of 200 μg selenium, daily for three months. Intervention 2: control: received one capsule of placebo daily for three months. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is Undecided - It is not yet known if there will be a plan to make this available