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IRCT2017031121965N6 IRCT 2017-04-21 Vice chancellor for research, Guilan University of Medical Sciences The effect of current stimulation and drug therapy on obsessive compulsive disorder - Comparing Transcranial direct current stimulation with and without drug therapy on symptoms of patient with obsessive compulsive disorder: a Clinical trial 2017-03-11 anticipated 40 Complete https://irct.ir/trial/19079 interventional Randomization: N/A, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Other design features: -. 3 obsessive – compulsive disorder. Intervention 1: Intervention Group 1: Twenty medical treatment - resistant patients suffering from obsessive compulsive disorders will be entered in this group. They will receive brain electrical stimulation (Transcranial direct current stimulation) while getting no medication. Therapy will be carried out in four thirty-minute sessions with one-week interval between each two sessions and music will be played to calm the patients during electrical stimulation. Follow up visits will be one and three month later. Comparing to the other noninvasive stimulation, TDCS is a new and noninvasive brain electrical stimulation method that is safe, low cost and simply designed in order to use in outpatient settings. Intervention 2: Intervention Group 2: Twenty medical treatment - resistant patients suffering from obsessive compulsive disorders will be entered in this group. Treatment consists of sufficient dose of Serotonin reuptake inhibitors (SSRI), Fluoxetine 80 mg or Setraline 200 mg, daily in combination with brain electrical stimulation. Therapy will be carried out in four thirty-minute sessions with one-week interval between each two sessions and music will be played to calm the patients during electrical stimulation. Follow up visits will be one and three month later. Comparing to the other noninvasive stimulation, TDCS is a new and noninvasive brain electrical stimulation method that is safe, low cost and simply designed in order to use in outpatient settings.
public Dr Kiomars Najafi
Shafa educational and remedial center, 15 Khordad avenue, Rasht, Iran
Rasht Iran (Islamic Republic of) 41939-55599 +98 13 3366 6268 Kkiomars@yahoo.com Guilan University Of Medical Sciences scientific Dr Kiomars Najafi
Shafa educational and remedial center, 15 Khordad avenue, Rasht, Iran
Rasht Iran (Islamic Republic of) 41939-55599 +98 13 3366 6268 Kkiomars@yahoo.com Guilan University Of Medical Sciences Iran (Islamic Republic of) Inclusion criteria: Patients with obsessive compulsive disorder; minimum score of 16 form YBOCS; aged between 18-55 years. Exclusion criteria: Antiepileptic drug therapy in the previous 6 months; neurologic disease; pregnancy; low intelligence quotient; head injury; any metallic instrument in brain or skull. 18 years 55 years Both F42 Obsessive-compulsive disorder Treatment - Other Treatment - Other Intervention Group 1: Twenty medical treatment - resistant patients suffering from obsessive compulsive disorders will be entered in this group. They will receive brain electrical stimulation (Transcranial direct current stimulation) while getting no medication. Therapy will be carried out in four thirty-minute sessions with one-week interval between each two sessions and music will be played to calm the patients during electrical stimulation. Follow up visits will be one and three month later. Comparing to the other noninvasive stimulation, TDCS is a new and noninvasive brain electrical stimulation method that is safe, low cost and simply designed in order to use in outpatient settings. Intervention Group 2: Twenty medical treatment - resistant patients suffering from obsessive compulsive disorders will be entered in this group. Treatment consists of sufficient dose of Serotonin reuptake inhibitors (SSRI), Fluoxetine 80 mg or Setraline 200 mg, daily in combination with brain electrical stimulation. Therapy will be carried out in four thirty-minute sessions with one-week interval between each two sessions and music will be played to calm the patients during electrical stimulation. Follow up visits will be one and three month later. Comparing to the other noninvasive stimulation, TDCS is a new and noninvasive brain electrical stimulation method that is safe, low cost and simply designed in order to use in outpatient settings Obsessive – compulsive disorder. Timepoint: Measured time intervals will be before the treatment and one and three months after the treatment. Method of measurement: Yale-Brown test. Vice chancellor for research, Guilan University of Medical Sciences Approved 2016-10-30 Ethics committee of Guilan University of Medical Sciences Vice chancellor for research of Guilan University of Medical Sciences, the upper floor of Iran Radiator Representation, in front of the Sepah bank, West Shahid Beheshti Blvd. Rasht Iran (Islamic Republic of)