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IRCT2017060621910N3 IRCT 2017-06-16 Vice Chancellor for research of Isfahan University of Medical Sciense Evaluating the effect of high dose versus low dose of heparin in patency of peripherally inserted central catheter in very low birth weight infants in alzahra and shahid beheshti hospitals in Isfahan at 1395-1396 Optimal dose of heparin for patency of peripherally inserted central catheter 2015-12-01 anticipated 45 Complete https://irct.ir/trial/19053 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention, Other design features: The infants were randomly allocated to either the low dose or high dose group by a simple randomization method using a table of random numbers. N/A Condition 1: Neonatal Sepsis. Condition 2: Intra Ventricular Hemorrhage. Condition 3: Catheter Related Sepsis. Condition 4: Phlebitis. Intervention 1: In Intervention Group we prescribed 1/5 u/kg/h of Heparin Via PICC. Intervention 2: In Control Group we prescribed ./5 u Heparin/1 cc of Serum Via PICC.
public Ladan Salamaty
Pediatric office, Imam hosein hospital, Imam khomeini street,
Isfahan Iran (Islamic Republic of) 00 ladan_salamaty@yahoo.com Isfahan University of Medical Sciences scientific Behzad Barekatain
Nom 302, Arian apartment building, Mehran ave, Moshtagh st, Isfahan
Isfahan Iran (Islamic Republic of) +98 31 3261 6670 b_barekatain@med.mui.ac.ir Isfahan University of Medical Scienses Iran (Islamic Republic of) Iran (Islamic Republic of) Inclusion criteria: preterm infants with birth weight less than 1500 gram; An informed consent obtained from patients parents; infant needs total parentral nutrition; long-term IV medication administration; administration of hyperosmolar IV fluids. Exclusion criteria: Skin infection at insertion site; uncorrected bleeding diathesis; ongoing bacteremia or fungal infection; follow up impossibility during study. no limit 1 month Both P36.9 P52.9 T82.9 T82.8 Bacterial sepsis of newborn, unspecified Intracranial (nontraumatic) haemorrhage of fetus and newborn, unspecified Unspecified complication of cardiac and vascular prosthetic device, implant and graft Other specified complications of cardiac and vascular prosthetic devices, implants and grafts Prevention Prevention In Intervention Group we prescribed 1/5 u/kg/h of Heparin Via PICC In Control Group we prescribed ./5 u Heparin/1 cc of Serum Via PICC Duration of Catheter Patency. Timepoint: Daily. Method of measurement: With Normal Saline and 5 cc Syringe. Catheter Related Sepsis. Timepoint: during Study. Method of measurement: Culture of Catheter Tip. Intra Ventricular Hemorrahge. Timepoint: 3th and 14th and 21th days. Method of measurement: Brain Sonography. Phlebitis. Timepoint: During Study. Method of measurement: Observation and Physical Examination. Sepsis. Timepoint: During Study. Method of measurement: Clinical Sign and Blood Culture. Vice Chancellor for research of Isfahan University of Medical Sciense Approved 2015-11-02 Ethics committee of Isfahan University of Medical Sciense Hezarjerib boulevard, Isfahan University of Medical Sciense Isfahan Iran (Islamic Republic of)