IRCT2015040821658N1 IRCT 2016-03-08 Investigator The comparison of the effect topical mouth rinse and chamomile mouthwash on chemotherapy-induced mucositis The comparison between topical mouth rinse and chamomile mouthwash on chemotherapy-induced mucositis in children with cancer referred to 17 shahrivar hospital in Rasht. 2015-07-23 anticipated 62 Complete https://irct.ir/trial/18923 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention. N/A Condition 1: Mucositis. Condition 2: Acute lymphoblastic leukemia. Intervention 1: In the experimental group for rinsing with mouthwash position according to the doctor, the nurse pills powder first and then with sodium bicarbonate and normal saline composition becomes half the patients are given a day before chemotherapy for a week, every day after brushing three times a day (morning, afternoon, evening) and every 10 cc without diluting gargle for a minute and they will not eat up an hour later than the previous standard treatment doctor Apart from the use chamomile will continue treating. Intervention 2: Patients in the control group to wash the mouth of chamomile mouthwash in pharmacies( drops 30 ml mouthwash Matrica making Barij Essence Kashan )from the day before chemotherapy for a week, every day after brushing three times a day (morning, noon night) use. so that 15 drops of the solution diluted in 10 ml of water and gargle for a minute and they will not eat up an hour later And previous standard treatment, your doctor will continue with the exception of local mouthwash.