IRCT2015042021607N2 IRCT 2015-07-04 Vice Chancellor for research of Tehran University of Medical Sciences Assessment of ketogenic diet(KD) on blod lipid in patients with refractory epilepsy. Assesment of ketogenic diet effects on lipid profile in patients with refractory epilepsy. 2015-01-11 anticipated 33 Complete https://irct.ir/trial/18884 interventional Randomization: N/A, Blinding: Not blinded, Placebo: Not used, Assignment: Single, Purpose: Prevention, Other design features: In this study, patients suffering from refractory epilepsy are referred to Ketogenic Diet clinic. IN this clinic parents and patients,if possible, are provided with essential information and skills about side effects and advantages of this diet. N/A Refractory Epilepsy. In this study, patients suffering from refractory seizure are treated with classic KD. This type of treatment is continued according to the required response and tolerance .In Ketogenic Diet, 80 percent of calories are provided from fat and the rest from carbohydrates and proteins.Ketogenic diet has some complications. These complications include: nausea, vomiting, cinstipation, hyperlipidemia, renal stones, and heart failure. The risk of these complications has been not assessed adequately in Iran yet, so we evaluated patients in determined intervals.In this study,patients were followed clinically and by laboratory evaluations before and after treatment ,in tree months, six months, and 12months intervals.