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IRCT20150315021480N8 IRCT 2018-05-09 Vice chancellor for research of Mazandaran University of Medical Sciences The effect of intravenous magnesium sulfate as a complementary therapy to COPD Study of the effect of intravenous magnesium sulfate on clinical performance as a complementary therapy of the patients with COPD in the emergency department 2017-10-23 anticipated 100 Complete https://irct.ir/trial/18822 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Other design features: In this study, the randomization of random number table was used, Randomization description: Patients are divided to two groups using simple randomization . In this way, we place each patient to toss up a coin head and tail in the intervention or control group, Blinding description: Patients will not be informed of the type of the group they will be. Moreover, the pharmacist of the study will code the drugs (codes A, B) without the author's knowledge. Thus, the nurse and distributor will also be unaware of the name of the drug received. 3 Chronic obstructive pulmonary disease. Intervention 1: Intervention group: Magnesium sulfate (2%) Obiidi pharmaceutical company is mixed with 200 ml of normal saline and is given intravenous infusion intravenously in 20 minutes. Intervention 2: Control group: Normal saline 0.9% (Obeidi factory) is given 100 cc once, under slow given intravenous infusion intravenously. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is No more information
public Sepideh Amirifar
Emergency Medicine Department, Imam Khomeini Hospital, Amir Mazandarani Street, Sari, Iran
Sari Iran (Islamic Republic of) 4813656148 +91 11555084 sepidehamirifard@gmail.com Mazandaran University of Medical Sciences scientific Fatemeh Jahanian
Emergency Medicine Department, Imam Khomeini Hospital, Amir Mazandarani Street, Sari, Iran
Sari Iran (Islamic Republic of) 4813656148 00 sepidehamirifard@gmail.com Mazandaran University of Medical Sciences Iran (Islamic Republic of) All patients with chronic pulmonary obstruction with moderate severity. no limit no limit Both Patients who have the need for intubation. Patients who have a history of heart disease Patients who have a low level of consciousness Patients who received intravenous magnesium sulfate within the last 24 hours j44 j44 Treatment - Drugs Placebo Intervention group: Magnesium sulfate (2%) Obiidi pharmaceutical company is mixed with 200 ml of normal saline and is given intravenous infusion intravenously in 20 minutes Control group: Normal saline 0.9% (Obeidi factory) is given 100 cc once, under slow given intravenous infusion intravenously Number of breaths. Timepoint: Counting the number of breaths at the beginning of the study (before the intervention) and 45 minutes and 6 hours after starting magnesium sulfate. Method of measurement: We count the breath per one minute. Blood pressure. Timepoint: before intervention and 45 minutes and 6 hours after intervention. Method of measurement: We get blood pressure using a manometer portable . Vice chancellor for research of Mazandaran University of Medical Sciences Approved 2017-08-18 Ethics Committee of Mazandaran University of Medical Sciences Vice chancellor for research, Mazandaran University of Medical Sciences, Moalem Square, Sari, Iran Sari Mazandaran Iran (Islamic Republic of)