<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE trials [
<!ELEMENT trials (trial+)>

<!ELEMENT trial (main,contacts,countries,criteria,health_condition_code,health_condition_keyword,intervention_code,
          intervention_keyword,primary_outcome,secondary_outcome,secondary_sponsor,secondary_ids,source_support,ethics_reviews)>

<!ELEMENT main (trial_id,utrn?,reg_name,date_registration,primary_sponsor,public_title,acronym?,scientific_title,scientific_acronym?,
          date_enrolment,type_enrolment,target_size,recruitment_status,url?,study_type,study_design,phase,hc_freetext?,i_freetext?,results_actual_enrolment,results_date_completed,results_url_link,results_summary,           results_date_posted,results_date_first_publication,results_baseline_char,results_participant_flow,results_adverse_events,results_outcome_measures,results_url_protocol,results_IPD_plan, results_IPD_description)>
<!ELEMENT trial_id (#PCDATA)>
<!ELEMENT utrn (#PCDATA)>
<!ELEMENT reg_name (#PCDATA)>
<!ELEMENT date_registration (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT primary_sponsor (#PCDATA)>
<!ELEMENT public_title (#PCDATA)>
<!ELEMENT acronym (#PCDATA)>
<!ELEMENT scientific_title (#PCDATA)>
<!ELEMENT scientific_acronym (#PCDATA)>
<!ELEMENT date_enrolment (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT type_enrolment (#PCDATA)>
<!ELEMENT target_size (#PCDATA)>
<!ELEMENT recruitment_status (#PCDATA)><!-- Pending,Recruiting,Suspended,Complete,Other -->
<!ELEMENT url (#PCDATA)>
<!ELEMENT study_type (#PCDATA)><!-- interventional,observational -->
<!ELEMENT study_design (#PCDATA)>
<!ELEMENT phase (#PCDATA)>
<!ELEMENT hc_freetext (#PCDATA)>
<!ELEMENT i_freetext (#PCDATA)>
<!ELEMENT results_actual_enrolment (#PCDATA)>
<!ELEMENT results_date_completed (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_url_link (#PCDATA)>
<!ELEMENT results_summary (#PCDATA)>
<!ELEMENT results_date_posted (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_date_first_publication (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT results_baseline_char (#PCDATA)>
<!ELEMENT results_participant_flow (#PCDATA)>
<!ELEMENT results_adverse_events (#PCDATA)>
<!ELEMENT results_outcome_measures (#PCDATA)>
<!ELEMENT results_url_protocol (#PCDATA)>
<!ELEMENT results_IPD_plan (#PCDATA)>
<!ELEMENT results_IPD_description (#PCDATA)>


<!ELEMENT contacts (contact+)>
<!ELEMENT contact (type,firstname,middlename,lastname,address,city,country1,zip,telephone,email,affiliation)>
<!ELEMENT type (#PCDATA)><!-- Public,Scientific -->
<!ELEMENT firstname (#PCDATA)>
<!ELEMENT middlename (#PCDATA)>
<!ELEMENT lastname (#PCDATA)>
<!ELEMENT address (#PCDATA)>
<!ELEMENT city (#PCDATA)>
<!ELEMENT country1 (#PCDATA)>
<!ELEMENT zip (#PCDATA)>
<!ELEMENT telephone (#PCDATA)>
<!ELEMENT email (#PCDATA)>
<!ELEMENT affiliation (#PCDATA)>

<!ELEMENT countries (country2+)>
<!ELEMENT country2 (#PCDATA)>

<!ELEMENT criteria (inclusion_criteria,agemin,agemax,gender,exclusion_criteria)>
<!ELEMENT inclusion_criteria (#PCDATA)>
<!ELEMENT agemin (#PCDATA)>
<!ELEMENT agemax (#PCDATA)>
<!ELEMENT gender (#PCDATA)>
<!ELEMENT exclusion_criteria (#PCDATA)>

<!ELEMENT health_condition_code (hc_code+)>
<!ELEMENT hc_code (#PCDATA)>

<!ELEMENT health_condition_keyword (hc_keyword+)>
<!ELEMENT hc_keyword (#PCDATA)>

<!ELEMENT intervention_code (i_code+)>
<!ELEMENT i_code (#PCDATA)>

<!ELEMENT intervention_keyword (i_keyword+)>
<!ELEMENT i_keyword (#PCDATA)>

<!ELEMENT primary_outcome (prim_outcome+)>
<!ELEMENT prim_outcome (#PCDATA)>

<!ELEMENT secondary_outcome (sec_outcome+)>
<!ELEMENT sec_outcome (#PCDATA)>

<!ELEMENT secondary_sponsor (sponsor_name+)>
<!ELEMENT sponsor_name (#PCDATA)>

<!ELEMENT secondary_ids (secondary_id+)>
<!ELEMENT secondary_id (sec_id,issuing_authority)>
<!ELEMENT sec_id (#PCDATA)>
<!ELEMENT issuing_authority (#PCDATA)>

<!ELEMENT source_support (source_name+)>
<!ELEMENT source_name (#PCDATA)>

<!ELEMENT ethics_reviews (ethics_review+)>
<!ELEMENT ethics_review (status,approval_date,contact_name,contact_address,contact_phone,contact_email)>
<!ELEMENT status (#PCDATA)><!-- Not approved,Approved,NA -->
<!ELEMENT approval_date (#PCDATA)><!-- dd/mm/yyyy -->
<!ELEMENT contact_name (#PCDATA)>
<!ELEMENT contact_address (#PCDATA)>
<!ELEMENT contact_phone (#PCDATA)>
<!ELEMENT contact_email (#PCDATA)>
]>
<trials>
  <trial>
    <main>
      <trial_id>IRCT20150314021459N5</trial_id>
      <utrn></utrn>
      <reg_name>IRCT</reg_name>
      <date_registration>2018-02-13</date_registration>
      <primary_sponsor>Vice chancellor for Research and Technology, Iran University of Medical Sciences,</primary_sponsor>
      <public_title>The Effect of McKenzie exercises in treatment of anterior knee pain</public_title>
      <acronym></acronym>
      <scientific_title>Comparing the effect of exercise therapy with Mckenzie versus Common methods in treatment of patients with Anterior Knee Pain (AKP): A randomized controlled trial.</scientific_title>
      <scientific_acronym></scientific_acronym>
      <date_enrolment>2017-07-03</date_enrolment>
      <type_enrolment>anticipated</type_enrolment>
      <target_size>22</target_size>
      <recruitment_status>Complete</recruitment_status>
      <url>https://irct.ir/trial/18801</url>
      <study_type>interventional</study_type>
      <study_design>Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: This randomized study into intervention and control groups was conducted by using Random allocation rule. A total of 22 individuals were assigned to individual randomization units with numbers 1 and 2, including 11 number 1 for the intervention group, and 11 number 2 for the control group. They were placed in a draw box.Allocation concealment was done by Sequentially numbered, sealed, opaque envelopes. Subsequently, the envelopes were removed without replacement.</study_design>
      <phase>2-3</phase>
      <hc_freetext>Condition 1: Anterior Knee Pain. Condition 2: anterior knee pain.</hc_freetext>
      <i_freetext>Intervention2: First the subjects have physiotherapy including hot pack with defined TENS. The place for electrodes are according to acupuncture  points. Therapeutic exercise includes strengthening of extensor, abductor, external rotator muscles of hip and flexor and extensors of knee.Exercises starts with warm up (5 min walking) and ended with cool down (hamstring, quadriceps and gastrocnemious stretch, 5 sec hold, 3 times repeat) 1RM is determined without counterweight and untigravity,to the border between fatigue and pain Start with 50% 1RM, daily to ten days. training progreses with 20% 1RM. trunk strengthening exercises performes with swiss ball in three methods (supine with straight knees and feet on ball, supine with bent knees and feet on ball and sitting on ball and raise feet from the floor),holding the position 10 seconds to 2 minutes depending on the individual's tolerance . 2 times a day..</i_freetext>
      <results_actual_enrolment></results_actual_enrolment>
      <results_date_completed></results_date_completed>
      <results_url_link></results_url_link>
      <results_summary></results_summary>
      <results_date_posted></results_date_posted>
      <results_date_first_publication></results_date_first_publication>
      <results_baseline_char></results_baseline_char>
      <results_participant_flow></results_participant_flow>
      <results_adverse_events></results_adverse_events>
      <results_outcome_measures></results_outcome_measures>
      <results_url_protocol></results_url_protocol>
      <results_IPD_plan>No - There is not a plan to make this available</results_IPD_plan>
      <results_IPD_description>Justification or reason for not sharing IPD is Excessive conflict</results_IPD_description>
    </main>
    <contacts>
      <contact>
        <type>public</type>
        <firstname>Mojtaba Kamyab</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>Madadkaran Al., Shahnazari St., Madar Sq., Mirdamad Blvd</address>
        <city>Tehran</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>1545913187</zip>
        <telephone>+98 21 2225 8769</telephone>
        <email>kamyab@iums.ac.ir</email>
        <affiliation>Vice research, School of Rehabilitation Sciences, Iran University of Medical Sciences</affiliation>
      </contact>
      <contact>
        <type>scientific</type>
        <firstname>Mohammad Akbari</firstname>
        <middlename></middlename>
        <lastname></lastname>
        <address>School of Rehabilitation Sciences, Madadkaran Al., Shahnazari St., Madar Sq., Mirdamad Blvd.,</address>
        <city>Tehran</city>
        <country1>Iran (Islamic Republic of)</country1>
        <zip>1545913187</zip>
        <telephone>+98 21 2222 8052</telephone>
        <email>Akbari.Mo@Iums.Ac.Ir</email>
        <affiliation>Dept. of Physiotherapy, School of Rehabilitation Sciences, Iran University of Medical Sciences,</affiliation>
      </contact>
    </contacts>
    <countries>
      <country2>Iran (Islamic Republic of)</country2>
    </countries>
    <criteria>
      <inclusion_criteria>Their age is between 16 and 40 years old.
Have at least two months pain in front of knee.
The pain rate is at least 3 cm by virtue of linear Visual Analog Scale.
At least 2 of the questionnaire Kujala give a positive response.</inclusion_criteria>
      <agemin>16 years</agemin>
      <agemax>40 years</agemax>
      <gender>Both</gender>
      <exclusion_criteria>Dissatisfaction of patient in each step of the study
Having a history of real locking of the knee
Having a history of dislocation of the patella.
Having the joint inflammation.
Having active infections
The presence of any abnormalities in knee joint radiography
Having the ligament injuries.
Having the malignancy.
Having the actual length difference of the lower extremities.
Taking of any tranquilizer medication during the 48 hours before the evaluation.
The presence of any abnormalities in the chest, upper and lower extremities.
The previous history of physiotherapy for knee.</exclusion_criteria>
    </criteria>
    <health_condition_code>
      <hc_code>M95, M96, </hc_code>
      <hc_code></hc_code>
    </health_condition_code>
    <health_condition_keyword>
      <hc_keyword>Other disorders of the musculoskeletal system and connective tissue</hc_keyword>
      <hc_keyword></hc_keyword>
    </health_condition_keyword>
    <intervention_code>
      <i_code>Rehabilitation</i_code>
    </intervention_code>
    <intervention_keyword>
      <i_keyword>Intervention2: First the subjects have physiotherapy including hot pack with defined TENS. The place for electrodes are according to acupuncture  points. Therapeutic exercise includes strengthening of extensor, abductor, external rotator muscles of hip and flexor and extensors of knee.Exercises starts with warm up (5 min walking) and ended with cool down (hamstring, quadriceps and gastrocnemious stretch, 5 sec hold, 3 times repeat) 1RM is determined without counterweight and untigravity,to the border between fatigue and pain Start with 50% 1RM, daily to ten days. training progreses with 20% 1RM. trunk strengthening exercises performes with swiss ball in three methods (supine with straight knees and feet on ball, supine with bent knees and feet on ball and sitting on ball and raise feet from the floor),holding the position 10 seconds to 2 minutes depending on the individual's tolerance . 2 times a day.</i_keyword>
    </intervention_keyword>
    <primary_outcome>
      <prim_outcome>Pain. Timepoint: At the beginning of the study, 10 days and one month after the start of the study. Method of measurement: Linear scale VAS.</prim_outcome>
      <prim_outcome>Function. Timepoint: At the beginning of the study, 10 days and one month after the start of the study. Method of measurement: Kujala questionnaire.</prim_outcome>
      <prim_outcome>Range of motion of knee. Timepoint: At the beginning of the study, 10 days and one month after the start of the study. Method of measurement: Goniometer.</prim_outcome>
    </primary_outcome>
    <secondary_outcome>
      <sec_outcome>Lenght of the hamstring  muscles. Timepoint: At the beginning of the study, 10 days and one month after the start of the study. Method of measurement: Clinometer.</sec_outcome>
      <sec_outcome>Lenght of the quadriceps muscle. Timepoint: At the beginning of the study, 10 days and one month after the start of the study. Method of measurement: Clinometer.</sec_outcome>
      <sec_outcome>Hamstring muscle strenght. Timepoint: At the beginning of the study, 10 days and one month after the start of the study. Method of measurement: Hand Dynamometer.</sec_outcome>
      <sec_outcome>Quadriceps muscle strenght. Timepoint: At the beginning of the study, 10 days and one month after the start of the study. Method of measurement: Hand Dynamometer.</sec_outcome>
      <sec_outcome>The fear avoidance beliefs. Timepoint: At the beginning of the study, 10 days and one month after the start of the study. Method of measurement: FABQ questionnaire.</sec_outcome>
    </secondary_outcome>
    <secondary_sponsor>
      <sponsor_name></sponsor_name>
    </secondary_sponsor>
    <secondary_ids>
      <secondary_id>
        <sec_id></sec_id>
        <issuing_authority></issuing_authority>
      </secondary_id>
    </secondary_ids>
    <source_support>
      <source_name>Vice chancellor for Research and Technology, Iran University of Medical Sciences,</source_name>
    </source_support>
    <ethics_reviews>
      <ethics_review>
        <status>Approved</status>
        <approval_date>2017-05-22</approval_date>
        <contact_name>Ethics Committee of  Iran University of Medical Sciences,</contact_name>
        <contact_address>Vice chancellor for Research and Technology, Central headquarters of Iran university of Medical Sciences, between Hemmat and Sheykh fazl ollah High ways, Tehran Tehran Iran (Islamic Republic of)</contact_address>
        <contact_phone></contact_phone>
        <contact_email></contact_email>
      </ethics_review>
    </ethics_reviews>
  </trial>
</trials>
