IRCT2016011221412N2 IRCT 2016-05-21 Vice chancellor for research, Shahroud University of Medical Sciences Effect of soybean supplementation and regular aerobic exercise in water on mental and physical symptoms of premenstrual syndrome Effect of soybean supplementation and regular aerobic exercise in water on mental and physical symptoms of premenstrual syndrome (PMS) female students 2014-03-20 anticipated 92 Complete https://irct.ir/trial/18771 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Other design features: For elimination of the possibility of any probable bias due to the knowledge of patients and assessing physicians about the type of treatment we will perform a double blind study. Soybean supplementation and Elaeagnus angustifolia powder as placebo will be encapsulated and for this reason patients and assessing physicians do not have any knowledge about the type of treatment. Randomization will be performed by the Randlist software and every patient will be entered into four intervention groups. 2 Premenstrual Syndrome (PMS). Intervention 1: Contrtol group: patients with PMS (23 girls) which use placebo (one capsule filled with senjed powder for each day after lunch during 8 weeks). Intervention 2: Intervention group: single patients with PMS during 8 weeks will use of one capsule of soybean supplementation each day. Intervention 3: Intervention group: single patients (23 girls) with PMS and regular aquatic exercise during 8 weeks with 50-60% heart rate for 30 minutes. Intervention 4: Intervention group: patients with PMS (23 girls) and regular aquatic exercise with 50-60% heart rate for 30 minutes will use of one capsule of soybean supplementation each day during 8 weeks.