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IRCT2015020720986N1 IRCT 2015-03-07 Vice chancellor for research, Isfahan University of Medical Science Effect of mixed of garlic and lemon juice on hyperlipidemia Effect of garlic and lemon juice mixture on lipid profile and some cardiovascular risk factors in people 30-60 years old with hyperlipidemia. 2013-10-23 anticipated 120 Complete https://irct.ir/trial/18510 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. N/A Hyperlipidemia. Intervention 1: first group received 20 grams of garlic plus 1 tablespoon lemon juice daily. Intervention 2: forth group did not recive garlic and lemon juice during the intervention. Intervention 3: second group recived 20 gram of garlic, daily. Intervention 4: third group recived 1 tablespoon of lemon juice, daily.
public Negar Aslani
Department of Clinical nutrition, School of Nutrition and Food Sciences, Isfahan University of Medical Scienses, Hezar Jerib street, Isfahan
Isfahan Iran (Islamic Republic of) +98 31 3433 2929 negar_aslani@nutr.mui.ac.ir; negaraslani5@yahoo.com Isfahan University of Medical Sciences scientific Negar Aslani
Department Of clinical Nutrition, School Of Nutrition and Food Sciences, Isfahan University Of Medical Sciences, Hezar Jerib Street, Isfahan
Isfahan Iran (Islamic Republic of) +98 31 3433 2929 negar_aslani@nutr.mui.ac.ir; negaraslani5@yahoo.com Isfahan university of Medical Sciences Iran (Islamic Republic of) Subjects were eligible if they have a total cholesterol and LDL levels between 240-200 mmol/l and 160-100 mmol/l respectively. People should not be suffering from any other diseases, including heart problems, kidney, lung, thyroid disorders, gastrointestinal, rheumatoid arthritis and other liver problems such as hepatitis or fatty liver, pregnancy or lactating, no smoking, their weight may not change fast in the last two months, should not use drugs that affect blood sugar, blood fat, blood pressure and anti-inflammatory and not to have any sensitivity to garlic and lemon juice. Individual with a history of chronic disease, consuming medicine and flowing special regimen were excluded. 30 years 60 years Both E78.0 Disorders of lipoprotein metabolism and other lipidaemias Prevention Prevention Prevention Prevention first group received 20 grams of garlic plus 1 tablespoon lemon juice daily forth group did not recive garlic and lemon juice during the intervention second group recived 20 gram of garlic, daily third group recived 1 tablespoon of lemon juice, daily Total cholesterol. Timepoint: in the first of intervention and end of 8th week. Method of measurement: enzymatic, mg/dl. Serum low-density lipoprotein cholesterol (LDL-C) levels. Timepoint: Before intervention and at the end of 8th week. Method of measurement: Enzymatic, mg/dl. Serum hight-density lipoprotein cholesterol (HDL-C) levels. Timepoint: Before intervention and at the end of 8th week. Method of measurement: Enzymatic, mg/dl. Triglyceride. Timepoint: in the first of intervention and end of 8th week. Method of measurement: Enzyme colorimetric methods, mg/dl. Fibrinogen. Timepoint: Before intervention and at the end of 8th week. Method of measurement: Clauss method. Systolic blood pressure. Timepoint: Before intervention and at the end of 8th week. Method of measurement: mmHg, Mercurial sphygmomanometer. Diastolic blood pressure. Timepoint: Before intervention and at the end of 8th week. Method of measurement: mmHg, Mercurial sphygmomanometer. Body mass index. Timepoint: Before intervention and at the end of 8th week. Method of measurement: kg/m2, Weight/Height squar. Fasting blood sugar. Timepoint: Before intervention and at the end of 8th week. Method of measurement: Enzymatic, mg/dl. Weight. Timepoint: Before intervention and at the end of 8th week. Method of measurement: Scale, kilogram. Isfahan University of Medical Sciences, School of Nutrition-School Nutrition Research Center Vice chancellor for research, Isfahan University of Medical Science Isfahan University of Medical Sciences, School of Nutrition-School Nutrition Research Center Approved 2013-10-28 Ethical Committee of Isfahan University of Medical Sciences Isfahan University of Medical Sciences, Hezar jarib street Isfahan Iran (Islamic Republic of)