IRCT2015012620819N1 IRCT 2015-06-13 School of Nursing and Midwifery Tehran University of Medical Sciences Effect of laughter therapy on cancer patients The effects of laughter therapy program on fatigue and depression of cancer patients undergoing chemotherapy in cancer patients undergoing chemotherapy intervention group compared with the control group 2015-02-04 anticipated 90 Complete https://irct.ir/trial/18399 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Health service research, Other design features: How random is that the researcher with a coin toss after sampling, samples were placed in pairs and then toss on tap and the other one in the intervention group and the control group were placed. N/A Cancer. Intervention 1: The control group received only routine care check vital signs, the physician's instructions and monitoring chemotherapy drugs, blood factors and the routine tests will enjoy not done any intervention by the researcher. Intervention 2: Laughter Therapy package includes short funny comedy clips on a DVD from a site authorized and approved by the Department of Cultural and Educational School of Nursing and Midwifery Tehran that every two weeks to see samples They will be given a period of 25-30 minutes.