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IRCT2017011620523N2 IRCT 2017-02-25 Hamedan University of Medical Sciences The effect of laser therapy on gingival inflammation Comparison of the effect of low power Diode laser therapy and placebo on the amount of Interleukin 1 beta in gingival crevicular fluid after placement separators in orthodontic patients 2017-02-19 anticipated 30 Complete https://irct.ir/trial/18188 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment. N/A Gingival inflammation. Intervention 1: Intervention 1: Irradiation of Diode laser with 980 nanometer wavelength and 1.5 Watts power with pulse irradiation with pulse length of 1 millisecond and pulse distance of 1 millisecond on buccal and lingual surface of maxillary first molar. Intervention 2: Irradiation of off laser with the same movement on buccal and lingual surface of maxillary first molar.
public Sepideh Soheilifar
Shahid Fahmide street, Hamedan University of Medical Sciences, Dental Faculty
Hamedan Iran (Islamic Republic of) +98 81 3822 3750 se.soheilifar@gmail.com Hamedan University of Medical Sciences scientific Sara Soheilifar
Shahid Fahmide street, Hamedan University of Medical Sciences, Dental Faculty
Hamedan Iran (Islamic Republic of) +98 81 3822 3750 sara_soheilifar@yahoo.com Hamedan University of Medical Sciences Iran (Islamic Republic of) Inclusion criteria: Signing informed consent; Absence of active periodontal disease (probing depth less than 4 mm and lack of bleeding on probing in upper first molars); Absence of systemic disease. Exclusion criteria: Presence of coagulation disease; Presence of acute or chronic disease (Based on patient chart); Presence of auto-immune disease; Patients under immune-suppressive therapy or radiotherapy; Patients who consume antibiotics; Patients who consume corticosteroids or nonsteroidal anti-inflammatory drugs (NSAIDS); Pregnant women. 8. Patients under periodontal treatment or prolonged consumption of chlorhexidine 18 years 30 years Both K05 Gingivitis and periodontal diseases Treatment - Other Placebo Intervention 1: Irradiation of Diode laser with 980 nanometer wavelength and 1.5 Watts power with pulse irradiation with pulse length of 1 millisecond and pulse distance of 1 millisecond on buccal and lingual surface of maxillary first molar Irradiation of off laser with the same movement on buccal and lingual surface of maxillary first molar Amount of interleukin 1 beta in gingival crevicular fluid. Timepoint: Before placement of separator and 1 week later. Method of measurement: ELISA on gingival crevicular fluid. Bleeding point index. Timepoint: Before placement of separator and 1 week later. Method of measurement: Occurence of bleeding during the movement of periodontal probe in gingival sulcus. Gingival index. Timepoint: Before placement of separator and 1 week later. Method of measurement: Observation. Hamedan University of Medical Sciences Approved 2017-01-14 Ethics comitee of Hamedan University of Medical Sciences Shahid Fahmide street, Hamedan University of Medical Sciences Hamedan Iran (Islamic Republic of)