]>
IRCT138903252172N4 IRCT 2010-06-29 Vice chancellor for reasearch, Iran University of Medical Sciences Effect of valerian root extract on sleep disturbances in menopausal women referred to selected health centers affiliated to Iran University of Medical Sciences 1388 Effect of valerian root extract on sleep disturbances in menopausal women referred to selected health centers affiliated to Iran University of Medical Sciences 1388 2010-04-21 anticipated 100 Complete https://irct.ir/trial/1789 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Supportive. 1-2 Sleep disorders. Intervention 1: Intervention group, Sedamin, 530 mg capsule, twice daily for one month. Intervention 2: Control group, Starch, placebo capsule, twice daily for one month. http://www.ncbi.nlm.nih.gov/pubmed/21775910 Abstract<br /> OBJECTIVE:<br /> Sleep disturbances reduce the quality of life. About 50% of postmenopausal women experience sleep disturbances such as insomnia. Complementary and alternative medical therapies may be useful for the management of sleep disturbances among postmenopausal women. The aim of the present study was to evaluate the effects of valerian extract taken nightly on the improvement of sleep quality in postmenopausal women experiencing insomnia.<br /> METHODS:<br /> A randomized, triple-blind, controlled trial design was used for this study. Participants consisted of 100 postmenopausal women aged 50 to 60 years who were experiencing insomnia. A demographic data form and the Pittsburgh Sleep Quality Index were used to collect data. The women were randomly divided into two groups. Each group received either 530 mg of concentrated valerian extract or a placebo twice a day for 4 weeks. Descriptive and inferential statistics were used to analyze the data.<br /> RESULTS:<br /> A statistically significant change was reported in the quality of sleep of the intervention group in comparison with the placebo group (P < 0.001). Also, 30% of the participants in the intervention group and 4% in the placebo group showed an improvement in the quality of sleep (P < 0.001).<br /> CONCLUSIONS:<br /> Valerian improves the quality of sleep in women with menopause who are experiencing insomnia. Findings from this study add support to the reported effectiveness of valerian in the clinical management of insomnia.<br />
public Simin Taavoni
3rd Floor, No.12, Nadjmabady St. Kazeroon St. Mirdamad Ave
Tehran Iran (Islamic Republic of) 1919915375 00982182471000; 00982182471111 staavoni@iums.ac.ir; staavoni14@yahoo.com Nursing and Midwifery Faculty, Iran University of Medical Sciences scientific Simin Taavoni
3rd Floor, No.12, Nadjmabady St. Kazeroon St. Mirdamad Ave.
Tehran Iran (Islamic Republic of) 1919915375 00982182471000; 00982182471111 staavoni14@yahoo.com; staavoni@iums.ac.ir Nursing and Midwifery Faculty, Iran University of Medical Sciences Iran (Islamic Republic of) Iran (Islamic Republic of) Inclusion and Exclusion criteria: • Not having physical and psychological diseases which may cause sleep problems • Not to use tobacco, drugs and alcohol • Appearance of any physical illness and psychological disorder while in study • Significant change in sleep conditions such as travel, shift work, etc. • Taking any additional medication during the study • Not taking the drug under investigation for more than 7 days during the study 50 years 60 years Female F51.0, F51 Nonorganic sleep disorders Treatment - Drugs Placebo Intervention group, Sedamin, 530 mg capsule, twice daily for one month Control group, Starch, placebo capsule, twice daily for one month Sleep dysfunction score. Timepoint: Before intervention and one month after intervention. Method of measurement: Pittsburg Sleep Quality Index questionnaire. Vice chancellor for reasearch, Iran University of Medical Sciences Approved 2010-03-12 Nursing and Midwifery Faculty, Iran University of Medical Sciences Valiasr street, after mirdamad,rashid yasemi street Tehran Iran (Islamic Republic of)