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IRCT2014102819733N1 IRCT 2015-11-28 Vice chancellor for research, Dezful University of Medical Sciences Effect of semi sitting position on inflammatory factors after appendectomy Effect of semi sitting and supine position on serum levels of inflammatory factors in patients after appendectomy 2016-02-14 anticipated 120 Complete https://irct.ir/trial/17580 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Supportive. N/A Acute Appendicitis. Intervention 1: 1)The first intervention group patients after surgery in the supine position and will receive three doses of antibiotics as directed by physician and 2 Hours, 2 and 24 hours after surgery for inflammatory markers CRP, ESR, leukocytes, neutrophils will be evaluated using blood samples, as well as temperature. Intervention 2: 2)In the second intervention group patients after surgery in the supine position and will receive one dose of antibiotics as directed by their physician and 2 Hours, 2 and 24 hours after surgery for inflammatory markers CRP, ESR, leukocytes, neutrophils will be evaluated using blood samples, as well as temperature. Intervention 3: 3)In the third study, patients received three doses of antibiotics after surgery, according to the doctor and have a semi-upright position and 2 Hours, 2 and 24 hours after surgery for inflammatory markers CRP, ESR, leukocytes, neutrophils will be evaluated using blood samples, as well as temperature. Intervention 4: 4)In the fourth study, patients after surgery with a dose of antibiotics will have a semi-upright position and 2 Hours, 2 and 24 hours after surgery for inflammatory markers CRP, ESR, leukocytes, neutrophils will be evaluated using blood samples, as well as temperature.
public Mohammad Maniey
Next The Police Department, Azadgan Alley, Dezful
Dezful Iran (Islamic Republic of) +98 64 1626 9041 maniey.m@dums.ac.ir; ymadmoli@gmail.com Dezful University of Medical Sciences scientific Yaghoob Madmoli
Martyr Khodadady Alley, Number Eight, Masjed Soleyman
Masjed Soleyman Iran (Islamic Republic of) 6491853954 +98 61 4323 0999 nursenanda1390@gmail.com; ymadmoli@gmail.com Dezful University of Medical Sciences Iran (Islamic Republic of) Inclusion Criteria : All patients on the basis of history and physical examination and laboratory findings; the diagnosis of acute appendicitis underwent appendectomy be; People aged 10 to 50 years; Not addicted to drugs; there is no underlying disease that is caused by elevated inflammatory markers before surgery; Consent to participate in the study and blood; having full consciousness baseline; If the body's inflammatory factors in sample 2 hours before and 2 hours after surgery are higher than normal. Exclusion Criteria : Diabetes; cancer; patients who had normal appendicitis; Patients with a history of previous infections and antibiotic use during the past week, a history of allergy to cephalosporins; Patients receiving immunosuppressive such as corticosteroids and cytotoxic drugs or taking anti-inflammatory drugs; Patients release from the hospital earlier than 24 hours. 10 years 50 years Both K35 Acute Appendicitis Prevention Prevention Prevention Prevention 1)The first intervention group patients after surgery in the supine position and will receive three doses of antibiotics as directed by physician and 2 Hours, 2 and 24 hours after surgery for inflammatory markers CRP, ESR, leukocytes, neutrophils will be evaluated using blood samples, as well as temperature. 2)In the second intervention group patients after surgery in the supine position and will receive one dose of antibiotics as directed by their physician and 2 Hours, 2 and 24 hours after surgery for inflammatory markers CRP, ESR, leukocytes, neutrophils will be evaluated using blood samples, as well as temperature. 3)In the third study, patients received three doses of antibiotics after surgery, according to the doctor and have a semi-upright position and 2 Hours, 2 and 24 hours after surgery for inflammatory markers CRP, ESR, leukocytes, neutrophils will be evaluated using blood samples, as well as temperature. 4)In the fourth study, patients after surgery with a dose of antibiotics will have a semi-upright position and 2 Hours, 2 and 24 hours after surgery for inflammatory markers CRP, ESR, leukocytes, neutrophils will be evaluated using blood samples, as well as temperature. CRP. Timepoint: 2 Hours Before; 2 And 24 Hours After Intervention (reposition). Method of measurement: Blood Samples, Immuno-agglutination Assay. ESR. Timepoint: 2 Hours Before; 2 And 24 Hours After Intervention (reposition). Method of measurement: Blood Samples, Green Blot Method. Leukocytes. Timepoint: 2 Hours Before; 2 And 24 Hours After Intervention (reposition). Method of measurement: Blood Samples, Cell Count Method. Neutrophils. Timepoint: 2 Hours Before; 2 And 24 Hours After Intervention (reposition). Method of measurement: Blood Samples, Cell Count Method. Temperature. Timepoint: 2 Hours Before; 2 And 24 Hours After Intervention (reposition). Method of measurement: Mercury Thermometer. Vice chancellor for research, Dezful University of Medical Sciences Approved 2015-07-29 Ethics committee of Dezful University of Medical Sciences Next The Police Department, Azadegan Boulevard, Dezful Dezful Iran (Islamic Republic of)