IRCT2014101619554N1 IRCT 2015-04-02 Vice Chancellor for Research,Zanjan University of Medical Sciences The effect of Chlorella Volgaris versus Arthichoke on patients with NAFLD- A randomized clinical trial The effect of Chlorella Volgaris versus Arthichoke on patients with NAFLD- A randomized clinical trial 2014-03-20 anticipated 200 Complete https://irct.ir/trial/17473 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. 2-3 Fatty liver. Intervention 1: Intervention:30 patient as the control group only received treatment with metformin and vitamin E, The second group,30 patients were treated with Chlorella supplements and third group (30 patients),were treated with Arthichoke supplements.Patients are recommended to have daily 20 minutes of physical activity and diet 500 kcal less than the previous in a group that have BMI 30-35 and 300 kcal in BMI 25-30 as well as. Main outcom:After eight weeks of treatment is measured serum levels of liver enzymes (ALT) and its level is considered as a measure of treatment response. (Reduced serum levels of at least 3 times as the response to treatment). Intervention 2: In the control group, 30 patients receiving metformin 500 mg( is made of Eksir company) 2 times a day, after breakfast and dinner,also vitamin E 400 IU ( is made of Eksir company)once a day after lunch.Nutrition and exercise advice given to patients for 2 months.