IRCT2014090819037N1 IRCT 2014-10-10 Vice Chancellor for Research, Qazvin University of Medical Sciences Comparison of the Effect of Honey and Diphenhydramine on Children's Nocturnal Cough and Sleep Quality Comparison of the Effect of Two Kinds of Iranian Honey and Diphenhydramine on Nocturnal Cough and Sleep Quality in Coughing Children and Their Parents 2013-09-23 anticipated 150 Complete https://irct.ir/trial/17125 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Other design features: The patients who come to the pediatrics clinic will be randomly selected for each groups of the study by Random Allocation. 2-3 nocturnal cough due to acute upper respiratory tract infection. Intervention 1: Control group: Oral solution of Diphenhydramine HCl from Ramopharmin drug manufacturing company, Tehran, Iran, registered No. 1228056772 (Patients in this group receive their treatments within 30 minutes before going to sleep at two subsequent nights (two doses). Dosage: children aged 2 to 6 years receive 6.25 mg/dose (2.5 mL), children aged 6 to 12 years receive 12.5 mg/dose (5 mL)). Intervention 2: First intervention group Kimia Honey from Kimia company, Ardabil, Iran, registered No. 4916 (Patients in this group receive their treatments within 30 minutes before going to sleep at two subsequent nights (two doses). Dosage: children aged 2 to 6 years receive 6.25 mg/dose (2.5 mL), children aged 6 to 12 years receive 12.5 mg/dose (5 mL)). Intervention 3: Second intervention group: ShahdeGolha Honey from ShahdeGolha company, Khorasan-e Razavi, Iran, registered No. 73294 (Patients in this group receive their treatments within 30 minutes before going to sleep at two subsequent nights (two doses). Dosage: children aged 2 to 6 years receive 6.25 mg/dose (2.5 mL), children aged 6 to 12 years receive 12.5 mg/dose (5 mL)).