IRCT20140903019036N3 IRCT 2018-08-17 Tehran University of Medical Sciences Comparison of two chemotherapy regimens including carboplatin-paclitaxel and capecitabine-oxaliplatin in neo-adjuvant chemo-radiation of esophageal cancer Comparison of efficacy and adverse effects of two chemotherapy regimens including carboplatin-paclitaxel and capecitabine-oxaliplatin in neo-adjuvant chemo-radiation of esophageal cancer for patients who were referred to Imam Khomeini cancer institute during year 95-96 2018-03-21 anticipated 92 Complete https://irct.ir/trial/17124 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Randomization description: Before starting the study, 4 part blocks consisting A and B were generated randomly. Patients were assigned to blocks consecutively. Codes were belonged to two groups consist of carboplatin-paclitaxel or capecitabine-oxaliplatin and so patients were randomized to two groups. 2 Esophageal cancer. Intervention 1: Intervention group: chemotherapy with oxaliplatin (85 mg/m2, week 1, 3, 5) + capecitabine (625mg/m2, BD, day 1 to 5, weekly), during radiotherapy. Intervention 2: Control group: chemotherapy with carboplatin (AUC = 2) + Paclitaxel (50 mg/m2), weekly, during radiotherapy. No - There is not a plan to make this available Justification or reason for not sharing IPD is Data of other research maybe becomes at risk