]>
IRCT2014083018974N1 IRCT 2015-03-02 Vice chancellor for research, Kermanshah University of Medical Sciences Effects of dimenhydrinate in children with acute gastroenteritis Study of effect of oral dimenhydrinate in children with acute gastroenteritis 2014-12-22 anticipated 200 Complete https://irct.ir/trial/17087 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment. 2-3 acute gastroenteritis. Intervention 1: Dimenhydrinate 4 doses (1mg/kg dose max 200 mg/dose). Intervention 2: placebo doses (1 mg / kg / dose to 50 mg / dose) during 6 days per week.
public Reza Akramipour
Mohammad Kemanshahi Hospital, Helal Ahmar Ave
Kermanshah Iran (Islamic Republic of) +98 83 3721 8202 Akramipur20@yahoo.com Kermanshah university of medical sciences scientific Simin Gheini
Mohammad Kemanshahi Hospital, Helal Ahmar Ave
Kermanshah Iran (Islamic Republic of) +98 83 3721 8202 SiminGheini@yahoo.com, Kermanshah university of medical sciences Iran (Islamic Republic of) Inclusion Criteria: Diagnosis of acute gastroenteritis by Specialist Physicians, At least 5 episodes of vomiting in 12 Hours; Aged between 1 to 12 years. Exclusion criteria: Chronic medical conditions of pre-existing such as gastrointestinal disease; malignancy; metabolic; cardiac; endocrine and metabolism, immune or nervous disorder. Secondary diagnosis of suspected from abdominal surgery or Or gynecologic conditions, urinary tract infections; migraine or meningitis. The use of antiemetic therapy in the 48 hours before the visit to the emergency. Use of other drugs such as acetaminophen or ibuprofen in the last 48 hours. History of allergies or adverse reactions to dimenhydrinate. Severe loss of water and requires urgent treatment with intravenous fluids. Hematemesis or hematochezia. 1 year 12 years Both K52.9 Noninfective gastroenteritis and colitis, unspecified Treatment - Drugs Placebo Dimenhydrinate 4 doses (1mg/kg dose max 200 mg/dose) placebo doses (1 mg / kg / dose to 50 mg / dose) during 6 days per week The number of vomiting episodes. Timepoint: Within 24 hours after using the first dose of prescription medication. Method of measurement: visit. The number of episodes of diarrhea. Timepoint: Within 24 hours after using the first dose of prescription medication. Method of measurement: visit. Vice chancellor for research, Kermanshah University of Medical Sciences Approved 2013-12-17 Kermanshah University of Medical Sciences Ethics Committee Kermanshah University of Medical Sciences, Shahid Beheshti Bolvar, Kermanshah Kermanshah Iran (Islamic Republic of)