IRCT2014082718946N1 IRCT 2014-10-03 Vice chancellor for research, Tabriz University of Medical Sciences Effects of plasmapheresis on patients with unstable complex pelvic fracture and long bones Effects of plasmapheresis on respiratory condition and acidosis of patients with unstable complex pelvic fracture and long bones 2014-10-01 anticipated 12 Complete https://irct.ir/trial/17058 interventional Randomization: N/A, Blinding: Not blinded, Placebo: Not used, Assignment: Single, Purpose: Treatment. 0 (exploratory trials) Unstable complex fracture of pelvic or long bones.. Intervention group: Patients with unstable complex fracture of hip and long bones, who are admitted to intense care unit, will be examined to assess their respiratory status (Arterial blood gas, respiratory rate and respiratory distress) every day 6 am. Patients will undergo plasmapheresis after acquiring mentioned parameters. Two hours after plasmapheresis , patients will undergo mentioned examinations again. Patients will undergo plasmapheresis every 24 hours until their condition has not changed or their hemodynamic status has not deteriorated..