IRCT2016042717254N5 IRCT 2016-11-23 Tehran University of Medical Sciences The effects of green cardamom supplementation in type 2 diabetic patients The effects of green cardamom supplementation on blood pressure and endothelium function,blood glucose indices, lipids, oxidant and anti oxidant parameters, sirtuin-1, irisin, oxidised LDL, apolipoprotein A1 and B and paraoxonase in type 2 diabetic patients 2016-11-20 anticipated 80 Complete https://irct.ir/trial/15919 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Health service research, Randomization description: Using block randomization method, in which the assignment was done based on sex (male/female) and BMI (overweight/ obese). By using stratified randomization participants were matched based on sex and BMI into blocks. Therefore, the block size was 4. By using this method equal number of men and women as well as overweight and obese patients were assigned to green cardamom and rusk powder group. Random allocation sequence was generated by using Random allocation software: RAS. The allocation process of participants into cardamom and rusk powder groups was done by a third person who was not involved in the project directly, Blinding description: In this study is a a randomized, double-blind, placebo controlled clinical trial. The capsules were labeled as A or B to be delivered to the subjects by a third person who was not involved in the project directly and had the job to make the supplements. All placebo capsules were placed close to cardamom capsules to take cardamom smell. For doing this, the supplements were safely capsulated. Then a person who was not involved in the study, packaged the two types of supplements in the plastic bags and placed them close together in a covered box. After one week the capsules were packaged in the small containers to be delivered to the subjects. It was tested to see if the placebo capsules took the smells. N/A diabetes. Intervention 1: Green cardamom supplements are prepared as 0.5 gram capsules. 2 capsule per meal (3 gram daily) should be consumed for 10 weeks. Intervention 2: placebo (flour breadcrumbs) supplements are prepared as 0.5 gram capsules. 2 capsule per meal (3 gram daily) should be consumed for 10 weeks. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is No more information available