IRCT2014041017211N1 IRCT 2014-05-05 Hormozgan University of Medical Sciences Compare effectiveness of broad spectrum antibiotic prophylaxy (Azitromycin + Keflin) with Keflin to prevent of post C/S infection in ER of Dr. Shariaty Hospital patient since 2011 July till 2012 August. Compare effectiveness of broad spectrum antibiotic prophylaxy (Azitromycin + Keflin) with Keflin to prevent of post C/S infection in ER of Dr. Shariaty Hospital patient since 2011 July till 2012 August. 2011-07-23 anticipated 424 Complete https://irct.ir/trial/15881 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Prevention. N/A To prevent post C/S infection. Intervention 1: Control Group received Cephalotin 2gr IV and placebo 1gr oral. These drugs were given only one dose before surgery. These groups of patients were admitted under full supervisioning 48 hours after surgery, and if fever was observed in each one, then she must be due to more time under supervisioning for differential diagnosis of the fever. After discharging, all of these patients were followed up for any sign of fever, endometritis and wound infection, for a month. Patients themselves, nurses and gynecologist those who followed up the postoperative of patients were unaware of the group and kind of drugs given to patients. Intervention 2: Case group received Azithromycin and Cephalotin as a preoperative antibiotic prophylaxis. These drugs were given only one dose before surgery. These groups of patients were admitted under full supervisioning 48 hours after surgery, and if fever was observed in each one, then she must be due to more time under supervisioning for differential diagnosis of the fever. After discharging, all of these patients were followed up for any sign of fever, endometritis and wound infection, for a month. Patients themselves, nurses and gynecologist those who followed up the postoperative of patients were unaware of the group and kind of drugs given to patients.