IRCT2014062916229N3 IRCT 2015-01-24 Vice chancellor for research,, Tabriz University of Medical Sciences The impact of Allopurinol in acute myocardial infarction The impact of allopurinol versus placebo in patients with acute ST elevation myocardial infarction undergoing fibrinolytic therapy with streptokinase 2014-05-31 anticipated 146 Complete https://irct.ir/trial/15258 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Other design features: The trial is double blind, so neither the patients nor the investigator are aware of the type of administered drug (Allopurinol or placebo). Random drug list has been prepared by the governing board of the Center for Drug Research. 3 myocardial infarction. Intervention 1: Intervention 1: patients will receive four oral Allopurinol 100mg tablets when arriving at the emergency department, followed by one 100mg tablet daily for 4 weeks. Allopurinol is a xanthine oxidase inhibitor and decreases production of uric acid. Intervention 2: Intervention 2: Placebo tablets are similar in appearance with Allopurinol tablets,which patients will receive four oral tablets when arriving at the emergency department, followed by one tablet daily orally for 4 weeks. Allopurinol and Placebo tablets has prepared by Drug Applied Research Center of Tabriz University of Medical Sciences.