IRCT2014010616106N1 IRCT 2014-02-05 Iran Center for Dental Research, Shahid Beheshti Medical University Oral Sedation in children Comparing the sedative effect of oral Midazolam/Hydroxyzine vs Chloral hydrate/Hydroxizine in behavior control of 6-10 year old uncooperative children. 2010-10-11 anticipated 60 Complete https://irct.ir/trial/15164 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Other design features: Each patient was seen in two separate visits in order to allow a comparison on the same patient preventing any influential factor to interfere with the outcome. 4 Condition 1: Behavior Control at the Dental Clinics. Condition 2: Uncooperative behavior in dental clinic. Intervention 1: Chloral Hydrate (50 mg/kg) /Hydroxyzine (1 mg/kg) both suspension form were given to children of the case group (oral mode), 1/2 hour before treatment start along with full monitoring the vital signs every 15 minutes starting from thew drug administration time to the discharge stage. Intervention 2: Oral suspension of Midazolam(0.5 mg/kg) along side Hydroxyzine elexir (1mg/kg)was administered in Control session 30 minutes prior to the starting point of the dental treatment in one dose. All vital signs were monitored thoroughly and details were recorded for further analysis.