IRCT2013112015465N1 IRCT 2014-01-21 Shahid Beheshti Medical University, Faculty of Pharmacy Study of the Effect of N-acetylcysteine on Urinary Tract Infection in Children. Study of the Effect of N-acetylcysteine Compared with Placebo on Inflammation Biomarkers of Acute Pyelonephritis in Children. 2014-01-01 anticipated 64 Complete https://irct.ir/trial/14728 interventional Randomization: Randomized, Blinding: Triple blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Other design features: This study is a triple blind, placebo controlled trial. Patients, prescriber, researcher and statistical analyzer are blind in this trial. The main drug and placebo are very similar in terms of appearance, odor, flavor,....So they are Indistinguishable from each other by patients or prescriber. Coding of drugs will be done by another person other than prescriber, researcher and statistical analyzer. Codes are numbers 1-64. 3 Acute pyelonephritis. Intervention 1: Effervescent tablet of N-acethyl cystein 600 mg dosing according to weight, until 5 days. Dose for patients more than 30 kg: 1.5 tablet daily 8.5-30 kg: 1 tablet daily less than 8.5 kg: 70 mg/kg. Intervention 2: Placebo effervescent tablet of N-acethyl cystein 600 mg dosing according to weight, until 5 days. Dose for patients more than 30 kg: 1.5 tablet daily 8.5-30 kg: 1 tablet daily: more than 30 kg: 1.5 tablet daily 8.5-30 kg: 1 tablet daily less than 8.5 kg: 70 mg/kg.