]>
IRCT2017063015446N10 IRCT 2017-07-11 Ahvaz Jundishapur University Of Medical Science Evaluation of clinical and peak flowmetry of nebulized Ketamin in acute asthma attack Evaluation of clinical and peak flowmetry of nebulized Ketamin in acute asthma attack 2016-11-21 anticipated 240 Complete https://irct.ir/trial/14714 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. N/A Asthma. Intervention 1: In the case group, 1 mg / kg of ketamine is inhaled in 1 dose at 0 minuts. Intervention 2: in two group,2.5 mg inhaled albotrol. In 3 doses with a 20 minute interval. Intervention 3: In both intervention and control groups. Ipratropium 0.5 mg inhaler with a 20 minute interval in three doses.
public Dr. Hassan Motamed
Golestan hospital, Golestan st.
Ahvaz Iran (Islamic Republic of) +98 61 3374 3079 motamed-h@ajums.ac.ir Ahvaz Jundishapor University of Medicial Sciences scientific Dr. Hassan Motamed
Golestan hospital, Golestan st.
Ahvaz Iran (Islamic Republic of) +98 61 3374 3079 motamed-h@ajums.ac.ir Ahvaz Jundishapor University of Medicial Sciences Iran (Islamic Republic of) Inclusion criteria: At least 18 years of age and up to 65 years old, patients with complaints of acute shortness of breath have been referred to the emergency department and According to the early symptoms, asthma was diagnosed ( Triad shortness of breath;diffusion wheezing and cough ) Exclusion criteria: Patients with lungs disorder and asthmatic manifestations such as ILD ... Smokers with more than 10packs per year of smoking, history of chronic bronchitis, acute medical problem, coronary artery disease, cardiac arrhythmia, high intracranial pressure, women Pregnant and nebolizer beta-agonist treatment for the past 6 hours, and mild and severe asthma attack are excluded 18 years 65 years Both J45 Asthma Treatment - Drugs Treatment - Drugs Treatment - Drugs In the case group, 1 mg / kg of ketamine is inhaled in 1 dose at 0 minuts in two group,2.5 mg inhaled albotrol. In 3 doses with a 20 minute interval In both intervention and control groups. Ipratropium 0.5 mg inhaler with a 20 minute interval in three doses FEV1. Timepoint: At 0,20, 40, 60, 90,minutes Since the beginning of the intervention. Method of measurement: Litre, by spirometry. Peak Expiratory Flow Rate (PEFR). Timepoint: At 0,20, 40, 60, 90,minutes Since the beginning of the intervention. Method of measurement: Litre, by spirometry. Respiratory rate. Timepoint: Minutes 0, 20, 40, 60and 90 since the beginning of the intervention. Method of measurement: Counting of respiration in one minute. Pulse rate. Timepoint: Minutes 0, 20, 40, 60and 90 since the beginning of the intervention. Method of measurement: Counting of pulse in one minute. Blood pressure. Timepoint: Minutes 0, 20, 40, 60and 90 since the beginning of the intervention. Method of measurement: mmHg, by sphygmomanometer. Blood oxygen saturation levels (SpO2). Timepoint: Minutes 0, 20, 40, 60and 90 since the beginning of the intervention. Method of measurement: Percentage, by pulse oximeter. Ahvaz Jundishapur University Of Medical Science Approved 2017-06-16 Ahvaz Jundishapor University of Medicial Sciences Ahvaz Jundishapor University of Medicial Sciences, Golestan st. Ahvaz Iran (Islamic Republic of)