]>
IRCT201107011836N2 IRCT 2011-09-15 Kerman University of Medical Sciences Comparison between methadone and opium effectiveness in control of agitation due to withdrawal syndrome in opium addicted patients admitted to the ICU of Kerman Shaheed Bahonar Hospital Comparison between methadone and opium effectiveness in control of agitation due to withdrawal syndrome in opium addicted patients admitted to the ICU of Kerman Shaheed Bahonar hospital 2011-08-06 anticipated 60 Complete https://irct.ir/trial/1411 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. N/A opium addiction. Intervention 1: Intervention group take opium tincture to prevent withdrawal syndrome and reach Richmond scale to score0. Intervention 2: Control group take methadon syrup for prevention of withdrawal syndrome and getting score 0 of Richmond scale.
public Seyed Mojtaba Sohrevardi
Faculty of Pharmacy
Kerman Iran (Islamic Republic of) +98 913 451 2422 smsohrevardi@yahoo.com Kerman University of Medical Sciences scientific Seyed Mojtaba Sohrevardi
Faculty of Pharmacy,
Kerman Iran (Islamic Republic of) +98 34 1320 5001 smsohrevardi@yahoo.com Pharmaceutical Research Center Iran (Islamic Republic of) Patients who addicted to opium and admitted to the ICU and they can tolerate methadon syrup or opium tincture by oral or gavage include to the study. If acute renal failure or hepatic failure happen to patients they will excluded from the study. 18 years 60 years Both F11.2 Mental and behavioural disordes Treatment - Drugs Treatment - Drugs Intervention group take opium tincture to prevent withdrawal syndrome and reach Richmond scale to score0 Control group take methadon syrup for prevention of withdrawal syndrome and getting score 0 of Richmond scale Richmond agitation-sedation score. Timepoint: BID. Method of measurement: standard richmond sheet. Respiratory rate. Timepoint: Multiple. Method of measurement: Ventilator. Blood pressure. Timepoint: Every 3 hr. Method of measurement: Spyngomanometer. Heart rate. Timepoint: Multiple. Method of measurement: Cardiovascular monitoring system. Kerman University of Medical Sciences Approved 2011-08-05 Ethic committee of Kerman university of medical sciences Research advisory of KMU, Blvd jomhouri eslami Kerman Iran (Islamic Republic of)