IRCT2013100814333N10 IRCT 2013-10-22 Kermanshah University of Medical Sciences The efficacy of Rosa damascene extract in treatment of sexual dysfunction induced by Selective Serotonin Reuptale Inhibitors in men with Major Depressive Disorder The efficacy of use and without use of Rosa damascene extract in treatment of sexual dysfunction induced by Selective Serotonin Reuptale Inhibitors in men with Major Depressive Disorder 2013-10-23 anticipated 60 Complete https://irct.ir/trial/13946 interventional Randomization: N/A, Blinding: Triple blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment. N/A Sexual dysfunction. Intervention 1: The intervention group received 3 cc Rosa damascenes drop daily for 8 weeks which was equivalent to 17 mg citronellol. Intervention 2: The control group received 3cc distilled water (placebo) daily.

public

scientific Dr. Vahid Farnia

first of Dolatabad Boulvard,Eisar Squqre

Kermanshah Iran (Islamic Republic of) +98 83 1826 0700 vfarnia@kums.ac.ir Kermanshah University of Medical Sciences Iran (Islamic Republic of) Inclusion criteria: Patients with major depressive disorders according to DSM IV; and those who had been treated with a fixed dose of serotonin reuptake inhibitors for at least eight weeks; those who haven’t sexual disorder before begin the treatment and they affected sexual disorder with use of this medicines such as decrease of libido, erection disorder ,delay of orgasm or dis ability to become orgasm Exclusion criteria: presence of sexual dysfunction before taking serotonin reuptake inhibitors; presence of any systemic or psychiatric disorders , Thyroid disease and hyperprolactinemia or taking any medication which affects sexual activity; any history of drug or alcohol use during 6 recent months; those who have recently had significant changes in sexual activity due to their wife pregnancy, remarriage and divorce no limit no limit Male F52 Sexual dysfunction, not caused by organic disorder or disease Treatment - Drugs Placebo The intervention group received 3 cc Rosa damascenes drop daily for 8 weeks which was equivalent to 17 mg citronellol The control group received 3cc distilled water (placebo) daily Days libido. Timepoint: At the beginning, 4th and 8th the week of study. Method of measurement: Asking the patient. Libido. Timepoint: At the beginning, 4th and 8th the week of study. Method of measurement: Asking the patient. Erection times. Timepoint: At the beginning, 4th and 8th the week of study. Method of measurement: Asking the patient. Erection stiff. Timepoint: At the beginning, 4th and 8th the week of study. Method of measurement: Asking the patient. Erection hardness. Timepoint: At the beginning, 4th and 8th the week of study. Method of measurement: Asking the patient. Hardness of flow out of semen. Timepoint: At the beginning, 4th and 8th the week of study. Method of measurement: Asking the patient. The problem of semen Amount. Timepoint: At the beginning, 4th and 8th the week of study. Method of measurement: Asking the patient. The problem of lack of semen. Timepoint: At the beginning, 4th and 8th the week of study. Method of measurement: Asking the patient. Sexual Satisfaction. Timepoint: At the beginning, 4th and 8th the week of study. Method of measurement: Asking the patient. The problem of ability to become erect and keeping it. Timepoint: At the beginning, 4th and 8th the week of study. Method of measurement: Asking the patient. Serotonin reuptake inhibitors. Timepoint: At the beginning, 4th and 8th the study week of. Method of measurement: Asking the patient. Kermanshah University of Medical Sciences Approved 2010-09-23 Kermanshah University of Medical Sciences Building No.2, Shahid Beheshti, Vice Chancellor for Research Affairs, Kermanshah University of Medical Sciences Kermanshah Iran (Islamic Republic of)