IRCT2013073114237N1 IRCT 2013-09-05 Vice Chancellor for Research, Isfahan University of Medical Sciences Effect of soy flour enriched bread on cardiovascular diseases Effect of soy flour enriched bread consumption or regular weight loss diet on anthropometric indices, blood pressure and serum lipid profile and its association with apoE genotype in over weight/ obese women: a randomized controlled trial. 2012-09-28 anticipated 30 Complete https://irct.ir/trial/13875 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Crossover, Purpose: Treatment. 2 Obesity. Intervention 1: Soy bread group: energy requirement will be calculated according to equations suggested by the Institute of Medicine, Food and Nutrition Board. for weight loss 300-500 calorie of calculated energy will be reduced . person in this intervention were asked to replace 120gr of soy bread with usual bread intake or other cereal. macronutrient composition for all participants will be 50-60% as carbohydrate, 15-20% as protein and <30% as fat. Intervention 2: Usual diet: energy requirement for each participant will calculated based on equations suggested by the Institute of Medicine, Food and Nutrition Board. 300-500 calorie will reduced for weight loss. subject in this diet will asked to continue their usual bread intake and other cereal products and not to consume soy product. macronutrient composition in this group is similar to the soy bread group.