IRCT2014010714199N4 IRCT 2014-03-13 Vice chancellor for research, Iran University of Medical Sciences Intravenous acetaminophen and remifentanil on the airway response in endoscopic sinus surgery Comparison of intravenous acetaminophen and remifentanil on the airway response to tracheal tube in endoscopic sinus surgery, during and the end of anesthesia: a clinical trial study 2012-07-05 anticipated 70 Complete https://irct.ir/trial/13853 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention. 2-3 cough. Intervention 1: In the first group, Remifentanil infusion 0/1 µg/kg /min has continued since the nasal tampons were inserted by surgeon until trachea extubation. Intervention 2: In the second group, remifentanil infusion was discontinued at the last 20 minutes of operation and acetaminophen perfusion(1 gr diluted in 100 cc of normal saline solution with 50 cc syringes in the same remifentanil syringes) was started by pump.