IRCT2013071413987N1 IRCT 2013-11-01 Kermanshah University of Medical Sciences,vice chancellor for research Studying Effect of One Third, Two Third and Normal Saline Serum on Contrast Induced Nephropathy. Comparative Study of Effect of One Third, Two Third and Normal Saline Serum on Prevention of Contrast Induced Nephropathy in Patients Undergoing Cardiac Angiography. 2013-08-23 anticipated 100 Complete https://irct.ir/trial/13695 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention. N/A Contrast Induced Nephropathy. Intervention 1: Intervention1:A group of patients will be given sodium bicarbonate plus one third and two third serum randomly, with speed of 1 cc for each kg per hour one hour before, , during and up to 6 hours after angiography. Sodium Bicarbonate 7.5%, each 100 cc contains; 7.5 gram sodium bicarbonate, Iran-Samen Pharmaceutical Company. One third and two third serum, each 100 cc contains; 3.33 gram dextrose and 0.3 gram sodium chloride, Iran Pharmaceutical Products Company. Intervention 2: Intervention2: Second group of patients will be given sodium bicarbonate plus normal saline serum randomly, with speed of 1 cc for each kg per hour one hour before, , during and up to 6 hours after angiography. Normal saline 9%: each 100 cc contains 9 gram sodium chloride,Iran Pharmaceutical Products Company.