IRCT20090317001774N9 IRCT 2018-09-19 Kerman University of Medical Sciences Study lipase inhibitor and Alpha-glucosidase inhibitor in control of weight in obese patient Study on the effects of co-administration of lipase inhibitor and Alpha-glucosidase inhibitor in control of weight in obese patient 2018-03-21 anticipated 90 Complete https://irct.ir/trial/1352 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Randomization description: After obtaining consent, the patients are divided into three groups based on entering the study and the method of balanced block randomization with triple blocks. The first group received orlistat (three daily food supplements, 180 mg), the second group was orlistat-acarbose (orlistat 60 mg three times daily with food, 25 mg acarbose three times daily at the start of meal) and the group Control (multivitamin, weekly 1), Blinding description: The blinding of groups is divided by the expert of the research center which is not involved in the implementation of the plan, and is kept in the dark envelope in the package until the end of the design and final analysis at the research center. According to the traditional use group, there is no possibility of blindness for the physician and the patient. But randomization is done in the form of a balanced block randomization in binary groups and four blocks, and the statistician is blind compared to the groups. 2-3 Condition 1: . Condition 2: obesity. Intervention 1: First Intervention group: The recipient of Orlistat (three daily food supplements, 180 mg) for 6 months. Intervention 2: Second Intervention group: The recipient of Orlistat and Acarbose (Orlistate 60mg 3 times daily with food, 25mg acarbose three times daily at the start of meal) for 6 months. Intervention 3: Control group: placebo (Multivitamin, weekly 1) for 6 months. Undecided - It is not yet known if there will be a plan to make this available Justification or reason for indecision in sharing IPD is Decision after the completing of study