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IRCT2013050613239N1 IRCT 2013-09-21 Development Deputy of Avaz University Effect of scaling and root planing on salivary melatonin level Evaluation of scaling and root planing effects on salivary melatonin level in patients with chronic periodontitis 2013-09-16 anticipated 60 Complete https://irct.ir/trial/13163 interventional Randomization: Not randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. N/A Chronic periodontitis. Intervention 1: Scaling and root planning. Intervention 2: No intervention.
public Dr Leila Golpasand
Ahvaz University of Medical Sciences, Mehr street, Golestan
Ahvaz Iran (Islamic Republic of) +98 61 1552 7368 drleilagolpasand@yahoo.com Ahvaz University of Medical Sciences scientific Dr Leila Golpasand
Faculty of Dentistry, Ahvaz University of Medical Science, Mehr street, Golestan
Ahvaz Iran (Islamic Republic of) +98 61 1552 7368 drleilagolpasand@yahoo.com Faculty of Dentistry Iran (Islamic Republic of) Inclusin criteria: patients with severe periodontitis؛ patients with moderate periodontitis؛ patients with gingivitis؛ subjects with periodontal healthy. Exclusion criteria: periodontal treatment or antibiotic therapy within the last 3 months؛ presence of any systemic disease (e.g.,diabetes mellitus, asthma)؛ working in night shifts؛ xerostomia or any other disease of the salivary glands؛ less than 20 teeth؛ intake of any drug known to alter melatonin levels (e.g., for sleeping disorders) or to be immunosuppressive؛ usage of partial or total prosthesis؛ pregnancy؛ lactation؛ acute infection؛ immunodeficiency؛ history of radio- or chemotherapy؛ and any conditions necessitating antibiotic premedication for dental appointment. 18 years 65 years Both K05.3 Chronic periodontitis Treatment - Other Treatment - Drugs Scaling and root planning No intervention Melatonin. Timepoint: Before intervention. Method of measurement: Concentration. Severity of disease. Timepoint: After intervention. Method of measurement: Pocket depth. Development Deputy of Avaz University Approved 2012-11-19 Ahvaz University of Medical Sciences Mehr street, Golestan Ahvaz Iran (Islamic Republic of)