IRCT201201231760N15 IRCT 2012-02-22 Vice Chancellor for Research and Technology, Babol University of Medical Sciences The effect of plasma rich growth factor in treatment of molar class II furcation involvement The effect of plasma rich growth factor in treatment of molar class II furcation involvement 2012-01-21 anticipated 12 Other https://irct.ir/trial/1279 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. N/A molar class II furcation involvment. Intervention 1: Control group: in one site treatment with double layer of membrane alone the treatment interference with drug. Intervention 2: Intervention group: Treatment with PRGF gel like in furcation area that is covered with double layer membrane of biogide.The preparation of PRGF gel: PRGF that 500 microliter in every tube is rich of growth factor and 4 times accumulated. Pour the Plasma in empty tube and for change it to gel to use it to apply space maintainer under the membrane.50 microliter with pipet 50 microliter from calcium chloride for every cc from PRGF add to sterile tube, after mixing plasma with calcium chloride, pour it into the sterile glassy dish and close its door.