]>
IRCT2017011412642N25 IRCT 2017-01-24 Vice chancellor for research, Iran University of Medical Sciences The effect of depth of anesthesia on pain after surgery The effect of depth of anesthesia on pain after surgery in laparascopic cholesystectomy 2016-09-22 anticipated 60 Complete https://irct.ir/trial/12679 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention, Other design features: patients with due attention to file number pair and odd, were randomely divided into two groups. N/A general anesthesia. Intervention 1: In the first group (L group) after induction of anesthesia, anesthesia in order to maintain BIS between 35 and 45, propofol with dose of 75 to 150 micrograms per kilogram of body weight and remifentanil with dose of 0.1 to 0.3 micrograms per kilogram of body weight are used. Intervention 2: In the first group (H group) after induction of anesthesia, anesthesia in order to maintain BIS between 35 and 45, propofol with dose of 75 to 150 micrograms per kilogram of body weight and remifentanil with dose of 0.1 to 0.3 micrograms per kilogram of body weight are used.
public Poopak Rahimzadeh
Hazrat Rasool Hospital, Satarkhan Ave
Tehran Iran (Islamic Republic of) +98 21 6651 5001 p-rahimzadeh@tums.ac.ir Anesthesiology group of Iran University of Medical Science scientific Poopak Rahimzadeh
Hazrat Rasool Hospital, Satarkhan Ave
Tehran Iran (Islamic Republic of) +98 21 6651 5001 p-rahimzadeh@tums.ac.ir Anesthesiology group of Iran University of Medical Science Iran (Islamic Republic of) Inclusion criteria: Patient candidated for elective laparascopic cholesystectomy; patient with ASA I or II; Lack of malignancy or seizures; Lack of auditory problem; BMI<35; Lack of heart, pulmonary, liver and kidney failure; Lack of uncontrolled systemic disease; Lack of addiction; Lack of chronic pain and/or with any analgesic drug.Exclusion criteria: Prolongation of action for more than three hours; Conversion of laparoscopic surgery to laparotomy; patient death. 18 years 65 years Both Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure Prevention Prevention In the first group (L group) after induction of anesthesia, anesthesia in order to maintain BIS between 35 and 45, propofol with dose of 75 to 150 micrograms per kilogram of body weight and remifentanil with dose of 0.1 to 0.3 micrograms per kilogram of body weight are used In the first group (H group) after induction of anesthesia, anesthesia in order to maintain BIS between 35 and 45, propofol with dose of 75 to 150 micrograms per kilogram of body weight and remifentanil with dose of 0.1 to 0.3 micrograms per kilogram of body weight are used Heart rate. Timepoint: during surgery, before and after that. Method of measurement: with pulse oxymeter device and according to beat per minute. Need to analgesic drug. Timepoint: during 24 hours after surgery. Method of measurement: according to miligeram. Amount of pain. Timepoint: in recovery and 8,16 and 24hours after surgery. Method of measurement: with using of VAS score. Systolic and diastolic blood pressure. Timepoint: during surgery, before and after that. Method of measurement: Non-invasive barometer in mm Hg. Amount of nausea and vomitting. Timepoint: during 24 hours after surgery. Method of measurement: according to severity and score 0 to 3. Duration of surgery. Timepoint: from start of surgery to start of recovery. Method of measurement: according to minute. Vice chancellor for research, Iran University of Medical Sciences Approved 2015-06-24 Vice chancellor for research, Iran University of Medical Sciences Vice chancellor for research of Iran University of Medical Sciences, Hemmat Highway Tehran Iran (Islamic Republic of)