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IRCT2015013012642N12 IRCT 2015-02-27 Vice Chancellor for Research and Technology of Tehran University of Medical Sciences The effect of anesthetic drugs on blood pressure and heart rate changes in patients with diagnostic angiography Comparison of anesthesia method with combined ketamine / sevoflurane and combined propofol/ketamine and its efficacy on blood pressure and heart rate changes in patients with diagnostic angiography 2015-03-01 anticipated 60 Complete https://irct.ir/trial/12666 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention. 1-2 Effects of anesthetic drugs in diagnostic angiography. Intervention 1: in The first group, induction of anesthesia with intravenous injection ketamine with dose of one mg per killogeram and receive sevoflurane will started. After 3 minutes, Laryngeal mask airway will be inserted. Intervention 2: In the second group solution containing of 80 mg per liter ketamine / propofol and 0.1 mg per killogeram of the prepared solution was administered for induction of anesthesia then Anesthesia will performe with infusion of 0.01 mg per killogeram per minute of solution.Laryngeal mask will be inserted after 3 minutes.
public
scientific Behrang Nooralishahi
Keshavarz Boulevard, Doctor Mohamed Gharib St.
Tehran Iran (Islamic Republic of) 00 b-nooralishahi@sina.tums.ac.ir Department of Anesthesiology, Tehran University of Medical Sciences Iran (Islamic Republic of) inclusion criteria: ASA I,II, Children 2 to 8 years, Written consent from the parent exclusion criteria: patients with pulmonary, hepatic, renal and metabolic disease, Patients with a prior history of cardiac and thoracic surgery, Patients who need more airway support and pulmonary care 2 years 8 years Both T88.7 Unspecified adverse effect of drug or medicament Prevention Prevention in The first group, induction of anesthesia with intravenous injection ketamine with dose of one mg per killogeram and receive sevoflurane will started. After 3 minutes, Laryngeal mask airway will be inserted In the second group solution containing of 80 mg per liter ketamine / propofol and 0.1 mg per killogeram of the prepared solution was administered for induction of anesthesia then Anesthesia will performe with infusion of 0.01 mg per killogeram per minute of solution.Laryngeal mask will be inserted after 3 minutes Arterial oxygen pressure. Timepoint: Before and after induction of anesthesia. Method of measurement: artrial blood gaz analyzer device in mmHg. Blood Pressure. Timepoint: Before and after induction of anesthesia. Method of measurement: Non-invasive barometer in mm Hg. Arterial pressure of carbon dioxide. Timepoint: Before and after induction of anesthesia. Method of measurement: By the analyzer device in mmHg. Arterial pulmonary blood pressure. Timepoint: Before and after induction of anesthesia. Method of measurement: by angiography in mmHg. Vice Chancellor for Research and Technology of Tehran University of Medical Sciences Approved 2013-12-17 Research Ethics Committee of Tehran University of Medical Sciences Ghods Ave, Keshavarz Boulevard Tehran Iran (Islamic Republic of)