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IRCT2013022312573N1 IRCT 2013-08-18 School of Public Health, Tehran University of Medical effect of saline and albumin %5 on serum viscosity Comparison of serum viscosity between patients whom infused human serum albumin5% with the patients whom infused normal saline 2012-12-20 anticipated 56 Complete https://irct.ir/trial/12624 interventional Randomization: Randomized, Blinding: Single blinded, Placebo: Not used, Assignment: Parallel, Purpose: Health service research. N/A plasma viscosity. Intervention 1: IV infusion of normal saline over one hour in control group. Intervention 2: IV infusion of serum albumin 5% over one hour in intervention group.
public Dr. Mozhde Jalali
Tehran, Emam Khomeini Ave. Sina Hospital
Ttehran Iran (Islamic Republic of) +98 21 6634 8504 jalali_m@razi.tums.ac.ir Tehran University of Medical Science scientific Dr.Farhad Etezadi
Tehran
Tehran Iran (Islamic Republic of) +98 21 6634 8504 etezadi@tums.ac.ir Tehran University of Medical Science Iran (Islamic Republic of) Inclusion criteria: All patients with ASA class I and II in the range of 20 to 50 years old candidated for low to momerate risk minor surgery. Exclusion criteria: patients with a history of hypertension; diabetes mellitus; ischemic heart disease; coagulopathy; receiving anti coagulant and antiplatlate factor; patients with BMI highier than 30; surgery duration longer than 2 hours and large fluid shift( more than 60ml/kg crystalloid infusion needed) during surgery 20 years 50 years Both R70.1 Abnormal plasma viscosity Diagnosis Diagnosis IV infusion of normal saline over one hour in control group IV infusion of serum albumin 5% over one hour in intervention group Blood serum viscosity. Timepoint: before infusion of any fluid ,one hour after infusion of normal saline or albumin 5%. Method of measurement: 5cc of patient's serum was transfused with a rate of 1 ml per minute while a 3- way stop-cock placed at the exit of the syringe. The serum had two ways to pass through them: 1) a 23 gauge needle. 2) Through an extension tube which was filled with distilled water. The height of the column of the water in the extension tube in millimeter was recorded and the viscosity value calculated with loading this formula: η = (π p r4)/(8' Q l). 1)determine the serum viscosity by age.2) determine the serum viscosity by the type of anesthesia 3)detrimine the serum viscosity by the type of surgery. Timepoint: befor infusion of any fluid. Method of measurement: 5cc of patient's serum was transfused with a rate of 1 ml per minute while a 3- way stop-cock placed at the exit of the syringe. The serum had two ways to pass through them: 1) a 23 gauge needle. 2) Through an extension tube which was filled with distilled water. The height of the column of the water in the extension tube in millimeter was recorded and the viscosity value calculated with loading this formula: η = (π p r4)/(8' Q l). School of Public Health, Tehran University of Medical Approved 2013-01-23 Tehran University of Medical Science Central Department of Tehran University, 6th Floor, Qods Ave, keshavarz boulevard, Tel.: 02188987381-2 Tehran Iran (Islamic Republic of)