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IRCT2013021912531N1 IRCT 2013-07-01 Vice chancellor for research, Ahvaz Jundishapur University of Medical Sciences Comparison of analgesic effect of intra-articular and peri -articular injection of morphine and ketamine compound following arthrotomy surgery Comparison of analgesic effect of intra-articular and peri -articular injection of morphine and ketamine compound following arthrotomy surgery 2013-09-01 anticipated 50 Complete https://irct.ir/trial/12596 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention, Other design features: Patients are assigned randomly to 2 groups using a computerized allocation schedule for the coded syringes containing the study drugs. After randomization, the coded syringes are prepared by an anesthesiologist not involve in the administration of the drug, patient care and data collection. 2-3 Pain. Intervention 1: Drugs: 1-Ketamine: Dose: 0.5mg/kg Number of using: Once Factory name: Rotexmedica Manufacturing Country's Name: Germany Location prescribed: intra-articular Administration time: 10 minutes before the end of surgery 2- Morphin: Dose: 0.5 mg Number of using: Once Factory name: Daroupakhsh Manufacturing Country's Name: Iran Location prescribed: intra-articular Administration time: 10 minutes before the end of surgery. Intervention 2: Drugs: 1-Ketamine: Dose: 0.5mg/kg Number of using: Once Factory name: Rotexmedica Manufacturing Country's Name: Germany Location prescribed: peri-articular Administration time: 10 minutes before the end of surgery 2- Morphin: Dose: 0.5 mg Number of using: Once Factory name: Daroupakhsh Manufacturing Country's Name: Iran Location prescribed: peri-articular Administration time: 10 minutes before the end of surgery.
public Kamran Mahmodi
No. 12, Enghelab Chamber, Golestan Blvd.
Ahvaz Iran (Islamic Republic of) 6135733777 +98 61 1432 5879 mostafafatahi777@gmail.com Ahvaz Jundishapur University of Medical Sciences scientific Kamran Mahmodi
No. 12, Enghelab Chamber, Golestan Blvd
Ahvaz Iran (Islamic Republic of) 6135733777 +98 61 1432 5879 mostafafatahi777@gmail.com Ahvaz Jundishapur University of Medical Sciences Iran (Islamic Republic of) Inclusion criteria: the patient's satisfaction; age between 20 and 60 years old. Exclusion criteria: the lack of patient's satisfaction to spinal anesthesia; history of hypnotics or narcotics throughout 24 hours before the surgery; history of drug abuse, or alcohol- dependency; contraindication of morphin or Ketamine. 20 years 60 years Both R52.0 Acute pain Treatment - Drugs Treatment - Drugs Drugs: 1-Ketamine: Dose: 0.5mg/kg Number of using: Once Factory name: Rotexmedica Manufacturing Country's Name: Germany Location prescribed: intra-articular Administration time: 10 minutes before the end of surgery 2- Morphin: Dose: 0.5 mg Number of using: Once Factory name: Daroupakhsh Manufacturing Country's Name: Iran Location prescribed: intra-articular Administration time: 10 minutes before the end of surgery Drugs: 1-Ketamine: Dose: 0.5mg/kg Number of using: Once Factory name: Rotexmedica Manufacturing Country's Name: Germany Location prescribed: peri-articular Administration time: 10 minutes before the end of surgery 2- Morphin: Dose: 0.5 mg Number of using: Once Factory name: Daroupakhsh Manufacturing Country's Name: Iran Location prescribed: peri-articular Administration time: 10 minutes before the end of surgery Pain. Timepoint: 1, 2, 4, 6, 12 and 24 hour after surgery. Method of measurement: Visual Analogue Scale. Opioid Consumption. Timepoint: 24 hours after surgery. Method of measurement: Milligrams. Vice chancellor for research, Ahvaz Jundishapur University of Medical Sciences Approved 2013-04-20 Ethics committee of Ahvaz Jundishapur University of Medical Sciences No.12, Chamber Sadaf, Golestan Blvd Ahvaz Iran (Islamic Republic of)