IRCT2013010512007N1 IRCT 2013-01-26 Deputy of Research Kerman University of Medical Sciences Comparison of the effect of Diazepam and Etomidate on cardiovascular system after laryngoscopy and intubation Comparison of the effect of Diazepam and Etomidate on hemodynamic responses to laryngoscopy and intubation 2012-09-01 anticipated 180 Complete https://irct.ir/trial/12166 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment, Other design features: The patients will be assessed in two identical groups of Diazepam and Etomidate. Randomization is made through minimization which neutralizes the issue of age. In fact these two groups have an identical range of age. The mechanism of collecting data is a checklist which is filled through inspection, examination and reviewing documents. The first part of it is about demographic information and the second part is for recording our observations which documents hemodynamic condition of the patient in four steps (after lying on surgical bed, immediately after intubation, 5 and 10 minutes later). We collect these data by means of digital monitoring device. At the end of anesthesia the awareness of patient will be assessed as well. We have to mention that the resident of anesthesia is not in participation of evaluating hemodynamic values and a technician will documents them without awareness of injected drug. N/A intubation. Intervention 1: Intervention: Diazepam (each ampoule contains10mg/2ml , made by Kimidaroo/Iran) injecting IV with dosage of 0.4mg/kg before induction of anesthesia. Intervention 2: Control group: Etomidate (each ampoule contains20mg/10ml , made by Janssen-Cling/Australia) injecting IV and stat with dosage of 0.3mg/kg before induction of anesthesia.