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IRCT2013081111504N4 IRCT 2013-10-29 Vice Chancellor for Research of Semnan University of Medical Science accuracy and complication of D&C and endometrial biopsy in patient with abnormal uterine bleeding Comparison the accuracy and complication of D&C and endometrial biopsy in patient with abnormal uterine bleeding 2013-10-07 anticipated 110 Complete https://irct.ir/trial/11740 interventional Randomization: N/A, Blinding: Not blinded, Placebo: Not used, Assignment: Single, Purpose: Diagnostic. 2-3 Abnormal uterine bleeding. Diagnostic intervention is endometrial biopsy by pipelle and standard diagnostic reference is sampling by endometrial curettage. Both techniques are performed in the operating room and at the same time. First pipelle enter to uterine cavity without cervical dilatation and then rotate and retracted to get endometrial samples. These samples are labeled A. Then, standard diagnostic curettage will perform and samples are labeled B. Both samples are sent to a pathologist who is unaware from sample collection methods. The samples are evaluated and the results will compare. Diagnostic curettage report to be used as the gold standard..
public Masomeh Mahboob
Amir Al Momenin HospitalŲŒ Imam Hussein square
Semnan Iran (Islamic Republic of) +98 23 1446 0077 mehrdadzahmatkesh@sem-ums.ac.ir Semnan University of Medical Science scientific Dr. Sanam Moradan
Amir Al Momenin Hospital, Imam Hussein Square
Semnan Iran (Islamic Republic of) +98 23 1446 0077 smoradan@sem-ums.ac.ir Semnan University of Medical Science Iran (Islamic Republic of) Inclusion criteria: Women older 35 years who have abnormal uterine bleeding. Exclusion criteria: Pregnancy; hormonal disorders including thyroid, hepatic and renal diseases, lupus, diabetes; endometrial thickness less than 4 millimeter; lower genital tract infection. no limit no limit Female N93.9 Abnormal uterine and vaginal bleeding, unspecified Diagnosis Diagnostic intervention is endometrial biopsy by pipelle and standard diagnostic reference is sampling by endometrial curettage. Both techniques are performed in the operating room and at the same time. First pipelle enter to uterine cavity without cervical dilatation and then rotate and retracted to get endometrial samples. These samples are labeled A. Then, standard diagnostic curettage will perform and samples are labeled B. Both samples are sent to a pathologist who is unaware from sample collection methods. The samples are evaluated and the results will compare. Diagnostic curettage report to be used as the gold standard. Accuracy of endometrial biopsy. Timepoint: After biopsy. Method of measurement: Comparison with diagnostic curettage. Vice Chancellor for Research of Semnan University of Medical Science Approved 2013-08-11 Ethic Committee of Semnan University of Medical Sicense Central Department, Semnan University of Medical Sicense, Basidj Bulvard Semnan Iran (Islamic Republic of)