]>
IRCT2014090711398N7 IRCT 2014-11-30 Research Deputy of Iran University of Medical Sciences Comparative evaluation of the effect of two different fluid therapy regimen on the bowel motility return after surgery Comparative evaluation of the effect of two different fluid therapy regimen (crystalloid VS crystalloid + colloid) on the speed of bowel motility return after gastrointestinal resection & anastomosis surgery 2013-06-22 anticipated 100 Complete https://irct.ir/trial/11661 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Not used, Assignment: Parallel, Purpose: Prevention. 3 Ileus. Intervention 1: Intervention group: For the fluid therapy of the patients of this group, we will use a combination of crystalloid & colloid fluids. Where, colloid will be used to replace the third space loss and bleeding until reaching the transfusion limit, and crystalloid for the replacing the rest of the fluid needs. Intervention 2: In control group:Total calculated fluid need of patients will be replaced with crystalloid (normal saline & ringer lactate in 50:50 ratio).
public Hosein Reza Dehghan MD.
Anesthesiology Department, Firoozgar Hospital, Beh-afrin St, Karim Khan Av.
Tehran Iran (Islamic Republic of) +98 21 8894 6762 dhoseinreza@gmail.com Iran University of Medical Sciences scientific Mohammad Reza Ghodraty MD.
Anesthesiology Department, Firoozgar Hospital, Beh-afarin St, Karim Khan Av.
Tehran Iran (Islamic Republic of) +98 21 8894 6762 mrghodrati@yahoo.comghodrati.mr@iums.ac.ir Iran University of Medical Sciences Iran (Islamic Republic of) Inclusion criteria: Patients candidated for resection & anastomosis of gastrointestinal surgery; Age between 18 - 60 years old; Patients with ASA physical status class I-III; Having consent for entry. Exclusion criteria: Age less than 18 & more than 60; Patients with ASA physical status over than III; Pregnant females; Patients with acute or chronic uncompensated cardiac insufficiency; Known coagulopathy; Hepatic insufficiency ( 2-3 times increase in liver enzymes); Renal insufficiency ( more than 50% rise in creatinine); Known gastroparesis & bowel motility disorders; Fatty patients with BMI over than 35 18 years 59 years Both K-56.0 Paralytic ileus Treatment - Other Treatment - Drugs Intervention group: For the fluid therapy of the patients of this group, we will use a combination of crystalloid & colloid fluids. Where, colloid will be used to replace the third space loss and bleeding until reaching the transfusion limit, and crystalloid for the replacing the rest of the fluid needs. In control group:Total calculated fluid need of patients will be replaced with crystalloid (normal saline & ringer lactate in 50:50 ratio) Ileus. Timepoint: Day after intervention. Method of measurement: Based on questionnare. Nausea & Vomiting. Timepoint: Day after intervention. Method of measurement: Based on questionnaire. Anastomosis leak. Timepoint: Day after intervention. Method of measurement: Based on clinical chart documents. Dehiscence. Timepoint: From day after intervention. Method of measurement: Based on clinical observation. Research Deputy of Iran University of Medical Sciences Approved 2013-09-07 Tehran University of Medical Sciences Main University building, Qods St. Keshavarz Blvd. Tehran Iran (Islamic Republic of)