]>
IRCT201510111674N12 IRCT 2015-10-21 Vice-Chancellery of Research and Technology, Shiraz University Of Medical Sciences Effectiveness of acute postoperative pain management of oral Lamotrigine after impacted third molar surgery. Postoperative pain management after impacted third molar surgery with perioperative oral Lamotrigine. 2015-10-23 anticipated 50 Complete https://irct.ir/trial/1153 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Other design features: It has been explained. 2 Impacted teeth. Intervention 1: Drug is administered with dose of 200 tablets of Lamotrigine orally with about 20 cc of water are given to the patient's study 1 hours before surgery. Intervention 2: The second group or control group received placebo with about 20 cc of water 1 hours before surgery.
public Hamid Reza Eftekharian
Shiraz University Of Medical Sciences, Shiraz Rajaei Hospital, Chamran Blvd., Shiraz
Shiraz Iran (Islamic Republic of) 7194815644 +98 71 3648 3783 eftekharhr@sums.ac.ir Shiraz School of Dentistry scientific Hamid Reza Eftekharian
Shiraz University Of Medical Sciences, Shiraz Chamran Hospital, Chamran Blvd., Shiraz
Shiraz Iran (Islamic Republic of) 7194815644 +98 71 3648 3783 eftekharhr@sums.ac.ir Shiraz School of Dentistry Iran (Islamic Republic of) Inclusion criteria included: The patients with systemic disease and no history of drug use, and willingness to cooperate in this study are enrolledØ› Exclusion criteria included known allergy to the study drug, hepatic and renal dysfunction and lack of signed informed consent will be excluded. 15 years 25 years Both K01.1 An impacted tooth is a tooth that has failed to erupt because of obstruction by another tooth. Treatment - Drugs Treatment - Drugs Drug is administered with dose of 200 tablets of Lamotrigine orally with about 20 cc of water are given to the patient's study 1 hours before surgery. The second group or control group received placebo with about 20 cc of water 1 hours before surgery. Intensity of postoperative pain. Timepoint: Immediately after surgery to 12 hours after surgery. Method of measurement: VAS. Patient's level of satisfaction. Timepoint: Immediately after surgery to 12 hours after surgery. Method of measurement: poor (0), moderate (1), good (2), and excellent (3). Post-operative complications of Lamotrigine. Timepoint: Immediately after surgery to 12 hours after surgery. Method of measurement: Nursing reports. Vice-Chancellery of Research and Technology, Shiraz University Of Medical Sciences Approved 2015-06-28 Ethics Committee of Shiraz University of Medical Sciences Shiraz University of Medical Sciences, Vice-Chancellery of Research and Technology, Zand Avenue, Shiraz Shiraz Iran (Islamic Republic of)