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IRCT2012100411004N1 IRCT 2013-07-09 Vice chancellor for research, Hamadan university of medical sciences Treatment of sleep disorders in patients with non-psychotic depressed Comparisons of healthy sleep education alone and combined with pharmacotherapy in the treatment of sleep disturbances in Non-psychotic depressed patients 2013-06-20 anticipated 90 Complete https://irct.ir/trial/11367 interventional Randomization: Randomized, Blinding: Not blinded, Placebo: Not used, Assignment: Parallel, Purpose: Treatment. 2-3 Depressive disorder. Intervention 1: Group 1: patients in group 1 will receive Lorazepam 1mg per night for 4 week. Intervention 2: Group 2: patients in group 2 will receive sleep healthy education face to face training and pamphlets. Intervention 3: Group 3: patients in group 3 will receive sleep healthy education face to face training and pamphlets and Lorazepam 1mg per night for 4 week. Sleep disturbances are nearly universal in psychiatric disorders, especially mood disorders. Research investigating associations between sleep and affective illness has largely focused on depression. This study evaluated the efficacy of lorazepam and Sleep hygiene education, alone or in combination on sleep in patients with non-psychotic depression. One hundred twenty patients with non-psychotic depression were randomly divided into 3 groups and either received Sleep hygiene education (n = 40), lorazepam (n = 40) and combined (n = 40) who were admitted to Farshchian hospital in Hamadan, Iran. The intervention lasted for 8 weeks. Pittsburgh Sleep Quality Index (PSQI) was used to measure of overall sleep quality. ANCOVA including and MANOVA were used to test intra-group and inter-group differences. Result showed that Sleep hygiene education, lorazepam and combined intervention were significant effect on sleep in patients with non-psychotic depression. There was no significant difference between Sleep hygiene educations and lorazepam. But found that intervention with a combination of Sleep hygiene educations and lorazepam had significant advantages over intervention with lorazepam or Sleep hygiene education alone (P
public Farshid Shamsaei
Nursing & Midwifery Faculty, Hamadan University of Medical Sciences, Shahid Fahmideh Bulv, Hamedan
Hamedan Iran (Islamic Republic of) 65178 +98 81 1823 2193 shamsaei68@yahoo.com Hamadan university of medical sciences scientific Farshid Shamsaei
Farshchian psychiatry hospital, Research center for behavioral disorders and substance abuse, Dibaj Ave.
Hamedan Iran (Islamic Republic of) +98 81 1827 1066 shamsaei@umsha.ac.ir Hamadan University of medical sciences Iran (Islamic Republic of) Inclusion criteria: Middle age group (35-60؛ No history of psychiatric disorders associated؛ No history of serious physical illness؛ Treated with SSRI antidepressants؛ The ability to read and write. Exclusion criteria included Electroconvulsive therapy؛ Having physical pain from chronic diseases؛ History of substance abuse. 35 years 65 years Both F30, F31, Mood [affective] disorders Treatment - Drugs Other Treatment - Other Group 1: patients in group 1 will receive Lorazepam 1mg per night for 4 week. Group 2: patients in group 2 will receive sleep healthy education face to face training and pamphlets. Group 3: patients in group 3 will receive sleep healthy education face to face training and pamphlets and Lorazepam 1mg per night for 4 week. Sleep disorders. Timepoint: Before and 4 week after. Method of measurement: Sleep Disorders Inventory. Depressive level. Timepoint: Before and four weeks after. Method of measurement: Hamilton Depression Scale. Vice chancellor for research, Hamadan university of medical sciences Approved 2013-05-20 Ethics Committee of Hamadan university of medical sciences Vice chancellor for research, Hamadan University of Medical Sciences, Shahid Fahmideh Bulv. Hamedan Iran (Islamic Republic of)