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IRCT2013082110900N2 IRCT 2013-09-22 Deputy of Research Kerman University of Medical Sciences Can lidocaine infusion during laparoscopic surgery reduce the pain? Evaluation of the effectiveness of intraoperative infusion of lidocaine on postoperative pain in laparoscopic cholecystectomy. 2013-09-23 anticipated 70 Complete https://irct.ir/trial/11308 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment, Other design features: After approving by Ethic Committee of Kerman University of Medical Sciences, informed consent will be obtained from the patients. The method of sampling is simple randomization which amongst studied members of community who are referred to operation rooms of Afzalipoor Hospital of kerman, one sample will be selected from the listed groups in the chances box by the patient accidentally. The medication is prepared by study leader and the anesthesiologist and technician who are responsible for taking care of the patient are blind to the medication as well as the patient. The preparation of patients in both group are similar and all the patients must be NPO for 8 hours before operation. 2 Cholecystectomy. Intervention 1: In intervention group Lidocaine (each ampoule contains 20 mg/ml Lidocaine, made by Daroopakhsh Co - Iran) with primary dose of 0.5 mg/kg and maintenance dose of 2 mg/kg/h is administered. Intervention 2: In control group placebo (normal saline) is administered.
public Hssein Sattari
Afzalipoor Hospital
Kerman Iran (Islamic Republic of) +98 34 1322 2250 hosattari@gmail.com Kerman University of Medical Sciences scientific Maryam Etminan
Afzalipoor Hospital
Kerman Iran (Islamic Republic of) +98 34 1322 2250 javakrd34@gmail.com Kerman University of Medical Sciences Iran (Islamic Republic of) Inclusion criteria are patient willingness to participation, ASA (American Society of Anesthesiologists) classification of I or II and elective laparoscopy. Exclusion criteria are history of sensitivity to local analgesics, long-lasting use of narcotics and steroids, pregnancy and history of cardiac or other chronic diseases and high blood pressure, age less than18 or more than 85, BMI more than 40, HR less than 50 and PR interval more than 0.2 sec. or any kind of cardiac block. 18 years 85 years Both K81 Cholecystitis Treatment - Drugs Placebo In intervention group Lidocaine (each ampoule contains 20 mg/ml Lidocaine, made by Daroopakhsh Co - Iran) with primary dose of 0.5 mg/kg and maintenance dose of 2 mg/kg/h is administered. In control group placebo (normal saline) is administered. Pain. Timepoint: before and after operation. Method of measurement: Visual Analogue Scale (VAS). Blood pressure. Timepoint: every 5 minutes and every 15 minutes in PACU. Method of measurement: digital monitoring device. Heart Rate. Timepoint: every 5 minutes and every 15 minutes in PACU. Method of measurement: digital monitoring device. Deputy of Research Kerman University of Medical Sciences Approved 2013-09-21 Ethics committee of Kerman University of Medical sciences Jomhoori boulevard Kerman Iran (Islamic Republic of)