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IRCT2012091610853N1 IRCT 2012-10-09 Vice-chancellor for research -Ahvaz Jondishapur University of Medical Science Effect of clonidine on hemodynamic changes and bleeding Effect of clonidine premedication on intraoperative Hemodynamic changes and Blood loss in mandibular fracture surgery . 2011-03-01 anticipated 86 Complete https://irct.ir/trial/11279 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Supportive. N/A Fracture of mandible. Intervention 1: In treatment group 1. Clonidine mg given orally one hour before surgery. Blood pressure, heart rate and mean arterial pressure one hour before surgery and during the specified times for 10 minutes and are recorded and bleeding at the end of the operation is calculated .This trial is a randomized, double-blind. Intervention 2: In the control group given a placebo an hour before surgery . Blood pressure, heart rate and mean arterial pressure one hour before surgery and during the specified times for 10 minutes and are recorded and bleeding at the end of the operation is calculated.
public Omid Ghasemzadeh
emam hospital department of oral and maxillofacial surgery
Ahvaz Iran (Islamic Republic of) +98 61 1372 7219 ghasemzadeho@yahoo.com Ahvaz University of Medical Sciences scientific Omid Ghasemzadeh
emam hospital
Ahvaz Iran (Islamic Republic of) +98 61 1372 7219 ghasemzadeho@yahoo.com Ahvaz University of Medical Sciences Iran (Islamic Republic of) Inclusion criteria : Groupings of men and women in the class I or II ASA; men and women between 15 to 35 years Exclusion criteria: Patients with a positive medical history of systemic diseases 15 years 35 years Both S02.6 Fracture of mandible Treatment - Surgery Treatment - Drugs In treatment group 1. Clonidine mg given orally one hour before surgery. Blood pressure, heart rate and mean arterial pressure one hour before surgery and during the specified times for 10 minutes and are recorded and bleeding at the end of the operation is calculated .This trial is a randomized, double-blind In the control group given a placebo an hour before surgery . Blood pressure, heart rate and mean arterial pressure one hour before surgery and during the specified times for 10 minutes and are recorded and bleeding at the end of the operation is calculated Blood loss and hemodynamic changes. Timepoint: preoperative and Intraoperative. Method of measurement: ml and mmH.g with manometer. The consumption of morphine and fentanyl, and remifentanil. Timepoint: intraoperative. Method of measurement: Micro g/ kg and mg/ kg. Vice-chancellor for research -Ahvaz Jondishapur University of Medical Science Approved 2011-03-01 Jondishapoor University of Medical Sciences Jondishapoor University of Medical Sciences ̦ Golestan Alley ̦ Ahvaz ̦ Khozestan Ahvaz Iran (Islamic Republic of)