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IRCT2012090810774N1 IRCT 2016-05-08 Vice chancellery of research,Shiraz University of Medical Sciences The effect of melatonin on the lipid levels Investigation of the effect of melatonin on the lipid levels in menopausal woman attending in selected Gynecology Clinics of Shiraz University of medical sciences, 1391 2013-01-20 anticipated 240 Complete https://irct.ir/trial/11190 interventional Randomization: Randomized, Blinding: Double blinded, Placebo: Used, Assignment: Parallel, Purpose: Treatment. 2 Menopause. Intervention 1: Intervention group: 3 milligram tablets of melatonin every night between 6 and 9 P.M. for 3 months. Intervention 2: Control group: 3 milligram tablets of placebo of melatonin every night between 6 and 9 P.M. for 3 month.
public Khadijeh Abdali
Namazi square, Fatemeh (PBUH) College of Nursing and Midwifery, Shiraz
Shiraz Iran (Islamic Republic of) +98 71 3647 4255 Abdalikh@sums.ac.ir Shiraz University of Medical Sciences scientific Khadijeh Abdali
Namazi Sq. Fatemeh (PBUH) College of Nursing and Midwifery
Shiraz Iran (Islamic Republic of) +98 71 3647 4255 abdalikh@sums.ac.ir Fatemeh (PBUH) College of Nursing and Midwifery, Shiraz Iran (Islamic Republic of) The inclusion criteria of the study: having general health based on the Goldberg’s questionnaire (achieving score less than 23); married women between 40 to 60 years old; not using vitamin supplements; not having used hormone therapy during the last 3 months; complete physical health in physical examinations; cessation of the menstrual cycle for at least 6 months; and FSH above 40 IU. The exclusion criteria of the study: A history of active liver, kidney, heart, thyroid, diabetes and inflammatory diseases; inability to continue drug use for any reason; unwillingness to continue participation in the study; and showing allergic reaction to the drug. In addition, if any of the conditions listed in the inclusion criteria were violated at any time, the volunteer would be excluded from the study. 40 years 60 years Female N95.1 Symptoms such as flushing, sleeplessness, headache, lack of concentration, associated with menopause Treatment - Drugs Treatment - Drugs Intervention group: 3 milligram tablets of melatonin every night between 6 and 9 P.M. for 3 months Control group: 3 milligram tablets of placebo of melatonin every night between 6 and 9 P.M. for 3 month Serum lipid. Timepoint: Before intervention,3 month after intervention. Method of measurement: Lipid of plasma were measured based on the international units. Changes in body mass index. Timepoint: Before intervention,3 month after intervention. Method of measurement: Dividing weight in kilograms by the square of height in meters. Vice chancellery of research,Shiraz University of Medical Sciences Approved 2012-12-23 Medical Research Ethics Committee of Shiraz University of Medical Sciences Shiraz University of Medical Sciences Shiraz Iran (Islamic Republic of)